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Quality control in pharmaceutical analysis : separation methods
Zdeněk Deyl
- Publikováno
- Amsterdam : Elsevier, 1997
- Stránkování
- 241 s.
Jazyk angličtina Země Nizozemsko
Knihovny.cz ISBN
0-444-82876-1
- Konspekt
- Farmacie. Farmakologie
- NLK Obory
- farmacie a farmakologie
It is difficult, if not impossible, to visualize pharmaceutical industry processes without appropriate analytical control, of which chromatographic and, more recently, capillary electromigration techniques constitute a considerable proportion. Problems such as deciding which separation technique will be the best, whether a chromatographic or an electrokinetically driven method is preferred, calibration procedures and method validation, identification of impurities by on-line hyphenation with techniques based on physicochemical principles other than chromatography and electrophoresis and assaying of basic physicochemical properties are all to be solved by the analytical chemist. Unintended errors can occur quite frequently.This volume covers all the above outlined areas, emphasizing those which the authors know from pharmaceutical research to cause problems in practice. The basic guidelines have been summarized along with the necessary theoretical background to help analysts select and apply modern chromatographic and electrokinetic methods of analysis in drug production and quality control and help them solve their particular problems.
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