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The design and analysis of sequential clinical trials
John Whitehead
- Published
- Chichester : John Wiley & Sons, repr. 2000
- Edition
- 2nd rev.ed
- Series
- Statistics in practice
- Pagination
- xii, 314 s.
Language English Country Great Britain
Document type Clinical Trial
Knihovny.cz ISBN
0-471-97550-8
- MeSH
- Clinical Trials as Topic MeSH
- Publication type
- Clinical Trial MeSH
- Conspectus
- Patologie. Klinická medicína
- NML Fields
- diagnostika
This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.
Bibliografie, index
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|---|---|---|
| Other libraries | Details | Services |
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