• MeSH
• mikro RNA genetika   MeSH
• molekulární biologie MeSH
• nádorové biomarkery MeSH
• nádory podle lokalizace MeSH
• polymorfismus genetický MeSH
• regulace genové exprese u nádorů MeSH
• regulace genové exprese MeSH

• Konspekt
• Biochemie. Molekulární biologie. Biofyzika
• NLK Obory
• biologie
• genetika, lékařská genetika
• onkologie
• NLK Publikační typ
• kolektivní monografie

MiRNA is an extremely fast growing field, and miRNA knowledge is now believed to be a pivotal element of cancer biology. It is already evident that the discovery of miRNA has created a paradigm shift in post-genomics biology, not only for scientists accustomed to traditional central dogma of molecular biology but also for researchers studying human diseases and accustomed to traditional genetics approach of studying one gene at the time. This book provides an introduction to the basic principles of miRNA biology, overview of miRNA significance in the hallmarks of cancer, experimental techniques used in miRNA research, and in special part - miRNAs importance in wide range of solid cancers with a special focus on its potential usage in molecular pathology, predictive oncology or as a novel therapeutic targets.

Obsahuje bibliografické odkazy a rejstřík

MicroRNAs biogenesis, function and decay / Ondrej Slaby and Jiri Sana -- MicroRNAs and genetic polymorphisms / Ondrej Slaby -- Methods for microRNAs discovery and detection / Ondrej Slaby and Jiri Sana -- MicroRNAs and the hallmarks of cancer / Ondrej Slaby -- MicroRNAs and colorectal cancer / Ondrej Slaby, Marek Svoboda and Rostislav Vyzula -- MicroRNAs and breast cancer / Martina Redova, Marek Svoboda and Rostislav Vyzula -- MicroRNAs and lung cancer / Jiri Sana and Ondrej Slaby -- MicroRNAs and prostate cancer / Jiri Sana -- MicroRNAs and renal cell carcinoma / Martina Redova, Jaroslav Michalek, and Ondrej Slaby -- MicroRNAs and hepatocellular cancer / Martina Redova -- MicroRNAs and pancreatic cancer / Martina Redova -- MicroRNAs and gastric cancer / Ondrej Slaby -- MicroRNAs and thyroid cancer / Martina Redova -- MicroRNAs and glioblastoma / Jiri Sana [et al.].