• MeSH
• analgetika farmakologie   MeSH
• anestetika * farmakologie   MeSH
• anestezie a analgezie MeSH
• farmakologie MeSH
• Publikační typ
• monografie MeSH

• Konspekt
• Farmacie. Farmakologie
• NLK Obory
• anesteziologie a intenzivní lékařství
• farmacie a farmakologie

"In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, second edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period"--Provided by publisher.

Obsahuje bibliografické odkazy a rejstřík

Machine generated contents note: Preface to the first edition; Preface to the second edition; Part I. Principles of Drug Action: 1. Pharmacodynamic principles of drug action; 2. G protein coupled receptors; 3. Other signalling pathways; 4. Signal transduction mechanisms: ion channels; 5. Principles of pharmacokinetics; 6. Principles of drug transformation; 7. Drug transport and transporters; 8. Target controlled infusions and closed loop administration; 9. Alternate routes of drug administration; 10. Principles of pharmacogenetics; 11. Pharmacodynamic drug interactions in anesthetic practice; 12. Pharmacoeconomics; Part II. Physiologic Substrates of Drug Action: 13. Sleep and consciousness; 14. Synaptic transmission; 15. Memory, learning and cognition; 16. Mechanisms of pain transmission and transduction; 17. Generation and propagation of action potentials; 18. Neuromuscular junction; 19. Vascular reactivity; 20. Cardiac rhythm; 21. Myocardial performance; 22. Autonomic function; 23. Physiology of immunity and inflammation; Part III. Essential Drugs in Anesthetic Practice: 24. Mechanisms of anesthetic action; 25. Pharmacokinetics of inhaled anesthetics; 26. Clinical pharmacology of inhaled anesthetics; 27. Pharmacokinetics of intravenous anesthetics; 28. Clinical pharmacology of intravenous anesthetics; 29. Benzodiazepines; 30. [alpha]-2 Agonists and other sedatives and amnestics; 31. Mechanisms of action of opioids; 32. Pharmacokinetics of opioids; 33. Clinical pharmacology of opioids; 34. Nonsteroidal anti-inflammatory drugs; 35. Other ion channel and receptor ligands for analgesia; 36. Local anesthetics; Machine generated contents note: Preface to the first edition; Preface to the second edition; Part I. Principles of Drug Action: 1. Pharmacodynamic principles of drug action; 2. G protein coupled receptors; 3. Other signalling pathways; 4. Signal transduction mechanisms: ion channels; 5. Principles of pharmacokinetics; 6. Principles of drug transformation; 7. Drug transport and transporters; 8. Target controlled infusions and closed loop administration; 9. Alternate routes of drug administration; 10. Principles of pharmacogenetics; 11. Pharmacodynamic drug interactions in anesthetic practice; 12. Pharmacoeconomics; Part II. Physiologic Substrates of Drug Action: 13. Sleep and consciousness; 14. Synaptic transmission; 15. Memory, learning and cognition; 16. Mechanisms of pain transmission and transduction; 17. Generation and propagation of action potentials; 18. Neuromuscular junction; 19. Vascular reactivity; 20. Cardiac rhythm; 21. Myocardial performance; 22. Autonomic function; 23. Physiology of immunity and inflammation; Part III. Essential Drugs in Anesthetic Practice: 24. Mechanisms of anesthetic action; 25. Pharmacokinetics of inhaled anesthetics; 26. Clinical pharmacology of inhaled anesthetics; 27. Pharmacokinetics of intravenous anesthetics; 28. Clinical pharmacology of intravenous anesthetics; 29. Benzodiazepines; 30. [alpha]-2 Agonists and other sedatives and amnestics; 31. Mechanisms of action of opioids; 32. Pharmacokinetics of opioids; 33. Clinical pharmacology of opioids; 34. Nonsteroidal anti-inflammatory drugs; 35. Other ion channel and receptor ligands for analgesia; 36. Local anesthetics;