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Synthesis of novel coumarin-based fluorescent probes
Ivana Kóšiová, Pavol Koiš
Language English Country Czech Republic
NLK
ProQuest Central
from 2005-01-01 to 2011
- MeSH
- Azides chemical synthesis MeSH
- Coloring Agents MeSH
- Research Support as Topic MeSH
- Fluorescent Dyes MeSH
- Coumarins chemical synthesis MeSH
- Molecular Probes MeSH
- Oligonucleotide Probes MeSH
- Triazoles chemical synthesis MeSH
We report on synthesis of new fluorescent probes suitable for site-specific incorporation into oligonucleotides. Coumarin derivatives were used as sensitive fluorescent labels and were attached to glycerol unit by two types of linkers as potential building blocks for oligonucleotide synthesis. Spectral characteristics of the functionalized coumarin building blocks were measured.
Grant č.1/3559/06 -- Grant č. APVV-51-046505 -- Grant č. 2003SP200280203
Bibliography, etc.Lit.: 41
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- $2 doi $a 10.1135/cccc20070996
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- $a Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, Bratislava
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- $a Grant č.1/3559/06 -- Grant č. APVV-51-046505 -- Grant č. 2003SP200280203
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- $a Lit.: 41
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- $a We report on synthesis of new fluorescent probes suitable for site-specific incorporation into oligonucleotides. Coumarin derivatives were used as sensitive fluorescent labels and were attached to glycerol unit by two types of linkers as potential building blocks for oligonucleotide synthesis. Spectral characteristics of the functionalized coumarin building blocks were measured.
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- $a molekulární sondy $7 D015335
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- $a kumariny $x chemická syntéza $7 D003374
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- $a fluorescenční barviva $7 D005456
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- $w MED00010973 $t Collection of Czechoslovak chemical communications $g Roč. 72, č. 8 (2007), s. 996-1004 $x 0010-0765
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