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Polymorphisme des insertions Alu chez les Berberes de Takrouna (Tunisie): une approche génétique a l'étude du peuplement de l'Afrique du Nord
Sabeh Frigi, Hajer Ennafaa, Mohamed Ben Amor, Lotfi Cherni, Amel Ben Ammar-El Gaaied
Language French Country Czech Republic
NLK
ProQuest Central
from 2001-01-01 to 1 year ago
ROAD: Directory of Open Access Scholarly Resources
from 1987
- MeSH
- Humans MeSH
- Polymorphism, Genetic genetics MeSH
- Check Tag
- Humans MeSH
- Geographicals
- Tunisia MeSH
To shed light on the study of the genetic structure of an isolated Berber community – Takrouna, seven polymorphic Alu insertions (ACE, APO-A1, F13B, TPA-25, PV92, B65 and D1) have been studied in a sample of 33 Berbers. The results show that genetic diversity, measured by heterozygosity, is relatively high in this community. It varied from 0.1896 concerning ACE to 0.4981 for TPAA-25. All loci are polymorphic. Thus, despite its small size, its antiquity and the endogamy realised, one would await a derived effect which reduces, even eliminates this diversity. However, it is not the case. Moreover, to better understand the genetic structure of this population, a multidimensional scaling analysis (MDS) and an AMOVA have been effected with other populations from the world. Results present that in spite of the isolation of Takrouna, this later conserved a North-African structure.
Lit.: 15
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- $a Polymorphisme des insertions Alu chez les Berberes de Takrouna (Tunisie): une approche génétique a l'étude du peuplement de l'Afrique du Nord / $c Sabeh Frigi, Hajer Ennafaa, Mohamed Ben Amor, Lotfi Cherni, Amel Ben Ammar-El Gaaied
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- $a Laboratoire de Génétique, Immunologie et pathologies Humaines Faculté des Sciences de Tunis, Université El Manar
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- $a Lit.: 15
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- $a To shed light on the study of the genetic structure of an isolated Berber community – Takrouna, seven polymorphic Alu insertions (ACE, APO-A1, F13B, TPA-25, PV92, B65 and D1) have been studied in a sample of 33 Berbers. The results show that genetic diversity, measured by heterozygosity, is relatively high in this community. It varied from 0.1896 concerning ACE to 0.4981 for TPAA-25. All loci are polymorphic. Thus, despite its small size, its antiquity and the endogamy realised, one would await a derived effect which reduces, even eliminates this diversity. However, it is not the case. Moreover, to better understand the genetic structure of this population, a multidimensional scaling analysis (MDS) and an AMOVA have been effected with other populations from the world. Results present that in spite of the isolation of Takrouna, this later conserved a North-African structure.
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