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Spontaneous ultraweak photon emission imaging of oxidative metabolic processes in human skin: effect of molecular oxygen and antioxidant defense system
A. Rastogi, P. Pospísil
Language English Country United States
Document type Journal Article, Research Support, Non-U.S. Gov't
NLK
PubMed Central
from 2009
Europe PubMed Central
from 2009 to 1 year ago
ROAD: Directory of Open Access Scholarly Resources
from 1998
PubMed
21950919
DOI
10.1117/1.3616135
Knihovny.cz E-resources
- MeSH
- alpha-Tocopherol metabolism MeSH
- Adult MeSH
- Photography MeSH
- Photons MeSH
- Skin Physiological Phenomena drug effects MeSH
- Glutathione metabolism MeSH
- Skin chemistry drug effects metabolism MeSH
- Ascorbic Acid metabolism MeSH
- Oxygen metabolism MeSH
- Humans MeSH
- Hand MeSH
- Free Radical Scavengers pharmacology MeSH
- Spectrophotometry instrumentation methods MeSH
- Ubiquinone analogs & derivatives metabolism MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
All living organisms emit spontaneous ultraweak photon emission as a result of cellular metabolic processes. In this study, the involvement of reactive oxygen species (ROS) formed as the byproduct of oxidative metabolic processes in spontaneous ultraweak photon emission was studied in human hand skin. The effect of molecular oxygen and ROS scavengers on spontaneous ultraweak photon emission from human skin was monitored using a highly sensitive photomultiplier tube and charged coupled device camera. When spontaneous ultraweak photon emission was measured under anaerobic conditions, the photon emission was decreased, whereas under hyperaerobic condition the enhancement in photon emission was observed. Spontaneous ultraweak photon emission measured after topical application of glutathione, α-tocopherol, ascorbate, and coenzyme Q10 was observed to be decreased. These results reveal that ROS formed during the cellular metabolic processes in the epidermal cells play a significant role in the spontaneous ultraweak photon emission. It is proposed that spontaneous ultraweak photon emission can be used as a noninvasive tool for the temporal and spatial monitoring of the oxidative metabolic processes and intrinsic antioxidant system in human skin.
References provided by Crossref.org
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