-
Je něco špatně v tomto záznamu ?
Extractions of isoquinoline alkaloids with butanol and octanol
J. Gregorová, J. Babica, R. Marek, H. Paulová, E. Táborská, J. Dostál,
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- benzofenantridiny izolace a purifikace MeSH
- butanoly chemie MeSH
- isochinoliny izolace a purifikace MeSH
- oktanoly chemie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Six different isoquinoline alkaloids (sanguinarine, chelerythrine, berberine, coptisine, allocryptopine, and protopine) were extracted by butanol and octanol from aqueous solution, pH 4.5. The samples were analyzed by HPLC. Butanol extraction was non-selective, alkaloids passed into organic phase in 83-98%. Octanol extraction provided more selective yields: sanguinarine 99%, chelerythrine 94%, berberine 18%, coptisine 16%, allocryptopine 7.5%, protopine 7%. Further, we tested octanol treatment of extract from Dicranostigma lactucoides. The octanol extraction yields were also selective: sanguinarine 98%, chelerythrine 92%, chelirubine 92.5%, protopine 6% and allocryptopine 3.5%. 6-Butoxy-5,6-dihydrosanguinarine and 6-butoxy-5,6-dihydrochelerythrine were prepared and their NMR and MS data are reported and discussed.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc12026472
- 003
- CZ-PrNML
- 005
- 20121207102535.0
- 007
- ta
- 008
- 120817e20100201ne f 000 0#eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.fitote.2010.01.020 $2 doi
- 035 __
- $a (PubMed)20117181
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a ne
- 100 1_
- $a Gregorová, Jana $u Department of Biochemistry, Faculty of Medicine, Masaryk University, Brno, Czech Republic. jgregorova@med.muni.cz
- 245 10
- $a Extractions of isoquinoline alkaloids with butanol and octanol / $c J. Gregorová, J. Babica, R. Marek, H. Paulová, E. Táborská, J. Dostál,
- 520 9_
- $a Six different isoquinoline alkaloids (sanguinarine, chelerythrine, berberine, coptisine, allocryptopine, and protopine) were extracted by butanol and octanol from aqueous solution, pH 4.5. The samples were analyzed by HPLC. Butanol extraction was non-selective, alkaloids passed into organic phase in 83-98%. Octanol extraction provided more selective yields: sanguinarine 99%, chelerythrine 94%, berberine 18%, coptisine 16%, allocryptopine 7.5%, protopine 7%. Further, we tested octanol treatment of extract from Dicranostigma lactucoides. The octanol extraction yields were also selective: sanguinarine 98%, chelerythrine 92%, chelirubine 92.5%, protopine 6% and allocryptopine 3.5%. 6-Butoxy-5,6-dihydrosanguinarine and 6-butoxy-5,6-dihydrochelerythrine were prepared and their NMR and MS data are reported and discussed.
- 650 _2
- $a benzofenantridiny $x izolace a purifikace $7 D053119
- 650 _2
- $a butanoly $x chemie $7 D000440
- 650 _2
- $a isochinoliny $x izolace a purifikace $7 D007546
- 650 _2
- $a oktanoly $x chemie $7 D000442
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Babica, Jan
- 700 1_
- $a Marek, Radek
- 700 1_
- $a Paulová, Hana
- 700 1_
- $a Táborská, Eva
- 700 1_
- $a Dostál, Jirí
- 773 0_
- $w MED00001802 $t Fitoterapia $x 1873-6971 $g Roč. 81, č. 6 (20100201), s. 565-8
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/20117181 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y m
- 990 __
- $a 20120817 $b ABA008
- 991 __
- $a 20121207102610 $b ABA008
- 999 __
- $a ok $b bmc $g 948514 $s 783818
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2010 $b 81 $c 6 $d 565-8 $e 20100201 $i 1873-6971 $m Fitoterapia $n Fitoterapia (Milano) $x MED00001802
- LZP __
- $a Pubmed-20120817/10/04
