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Management of antiplatelet therapy inpatients at risk for coronary StentThrombosis undergoing non-cardiac surgery
Z. Motovska,
Language English Country New Zealand
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
Grant support
NT11506
MZ0
CEP Register
Digital library NLK
Full text - Article
Source
NLK
ProQuest Central
from 2008-05-01 to 1 year ago
Nursing & Allied Health Database (ProQuest)
from 2008-05-01 to 1 year ago
Health & Medicine (ProQuest)
from 2008-05-01 to 1 year ago
- MeSH
- Aspirin administration & dosage MeSH
- Time Factors MeSH
- Blood Vessel Prosthesis adverse effects MeSH
- Surgical Procedures, Operative MeSH
- Inpatients MeSH
- Platelet Aggregation Inhibitors administration & dosage MeSH
- Drug Therapy, Combination MeSH
- Coronary Thrombosis etiology therapy MeSH
- Humans MeSH
- Pyridines administration & dosage MeSH
- Risk Factors MeSH
- Stents adverse effects MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Percutaneous coronary interventions (PCIs) have become the most commonly performed coronary revascularization procedures. At the same time, there is an increased likelihood that patients with intracoronary stents will need to undergo surgery. Two serious consequences emerge from this situation: (i) stent thrombosis in relation to discontinuation of antiplatelet therapy, and (ii) major bleeding in relation to continuation of antiplatelet therapy. The best solution to overcome the risks resulting from surgery performed in patients after stent implantation is to postpone the operation until after re-endothelialization of the vessel surface is completed. Expert recommendations advise that patients can be sent for non-cardiac surgery 3 months after bare-metal stent PCI and 12 months after drug-eluting stent PCI, with continuation of aspirin therapy. Difficult decisions regarding antiplatelet management arise when a patient that is still receiving dual antiplatelet therapy with aspirin and a thienopyridine has to undergo surgery that cannot be postponed. Discussions between the treating cardiologist, the surgeon and the anaesthesiologist about this situation are recommended in order to achieve a reasonable expert consensus.
References provided by Crossref.org
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- $a Percutaneous coronary interventions (PCIs) have become the most commonly performed coronary revascularization procedures. At the same time, there is an increased likelihood that patients with intracoronary stents will need to undergo surgery. Two serious consequences emerge from this situation: (i) stent thrombosis in relation to discontinuation of antiplatelet therapy, and (ii) major bleeding in relation to continuation of antiplatelet therapy. The best solution to overcome the risks resulting from surgery performed in patients after stent implantation is to postpone the operation until after re-endothelialization of the vessel surface is completed. Expert recommendations advise that patients can be sent for non-cardiac surgery 3 months after bare-metal stent PCI and 12 months after drug-eluting stent PCI, with continuation of aspirin therapy. Difficult decisions regarding antiplatelet management arise when a patient that is still receiving dual antiplatelet therapy with aspirin and a thienopyridine has to undergo surgery that cannot be postponed. Discussions between the treating cardiologist, the surgeon and the anaesthesiologist about this situation are recommended in order to achieve a reasonable expert consensus.
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