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Fibrous Dysplasia Presenting as a Cold Spot in 18F-FLT PET/CT Imaging
Z. Rehak, B. Bencsikova, I. Zambo, T. Kazda,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu kazuistiky, časopisecké články
- MeSH
- dideoxynukleosidy MeSH
- dospělí MeSH
- fibrózní dysplazie kosti diagnostické zobrazování MeSH
- fluorodeoxyglukosa F18 MeSH
- lidé MeSH
- os pubis diagnostické zobrazování MeSH
- PET/CT MeSH
- radiofarmaka MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
Fibrous dysplasia (FD) is a benign bone lesion in which normal bone marrow is replaced by fibro-osseous tissue. The usual high fluorodeoxyglucose (F-FDG) uptake in FD may lead to the misdiagnosis of bone malignancy. Herein, we describe the case of a 42-year old man with histologically verified FD of the pubic bone, which has been subsequently examined during follow-up for rectal cancer, using both F-FDG and fluorothymidine (F-FLT) PET/CT imaging. The FD lesion was characterized by a high uptake of F-FDG (hot spot) but very low uptake of F-FLT (cold spot) as compared with the contralateral unaffected pubic bone.
Citace poskytuje Crossref.org
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- $a Rehak, Zdenek $u From the *Department of Comprehensive Cancer Care, Faculty of Medicine, Masaryk University and Masaryk Memorial Cancer Institute, Zluty kopec, Brno, Czech Republic; †Department of Nuclear Medicine, PET Center, RECAMO, Masaryk Memorial Cancer Institute, Zluty kopec, Brno, Czech Republic; ‡1st Department of Pathological Anatomy, Faculty of Medicine, Masaryk University and St. Anne's University Hospital, Pekarska, Brno, Czech Republic; and §Department of Radiation Oncology, Faculty of Medicine, Masaryk University and Masaryk Memorial Cancer Institute, Zluty kopec, Brno, Czech Republic.
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- $a Fibrous dysplasia (FD) is a benign bone lesion in which normal bone marrow is replaced by fibro-osseous tissue. The usual high fluorodeoxyglucose (F-FDG) uptake in FD may lead to the misdiagnosis of bone malignancy. Herein, we describe the case of a 42-year old man with histologically verified FD of the pubic bone, which has been subsequently examined during follow-up for rectal cancer, using both F-FDG and fluorothymidine (F-FLT) PET/CT imaging. The FD lesion was characterized by a high uptake of F-FDG (hot spot) but very low uptake of F-FLT (cold spot) as compared with the contralateral unaffected pubic bone.
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