• Something wrong with this record ?

Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes

T. Pavlová, F. Zlámal, Z. Šplíchal, J. Tomandl, Z. Hodická, P. Ventruba, J. Bienertová-Vašků,

. 2018 ; 31 (14) : 1811-1818. [pub] 20170525

Language English Country England, Great Britain

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc19001262

OBJECTIVES: The aim of the study is to investigate differences in visfatin concentrations between mothers with term and preterm birth (PTB) and between mothers who delivered within seven days and after more than seven days following admission for PTB/preterm premature rupture of membranes (PPROMs). METHODS: Maternal peripheral blood and cord blood were collected from 56 mothers with PTB (31 with PPROM) and 71 mothers with term delivery (three with PPROM). RESULTS: Maternal visfatin concentration was significantly higher for given gestational age in PTBs compared to term deliveries (p = .021) and also in mothers who delivered within seven days after admission for PTB or PPROM, compared to those who delivered after more than seven days (p = .027; p = .039). Cord blood visfatin concentration was found to be decreased in preterm compared to term infants (p = .007). CONCLUSIONS: Visfatin in both maternal and fetal circulation may play an important role in the pathogenesis of PTB/PPROM and could be used to distinguish between women who will deliver in a short period of time after clinical presentation of PTB/PPROM and those who deliver later. Nevertheless, additional research is necessary in order to identify its direct involvement in PTB/PPROM.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19001262
003      
CZ-PrNML
005      
20190121120745.0
007      
ta
008      
190107s2018 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1080/14767058.2017.1328493 $2 doi
035    __
$a (PubMed)28482725
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Pavlová, Tereza $u a Department of Pathological Physiology, Faculty of Medicine , Masaryk University , Brno , Czech Republic. b Research Centre for the Toxic Compounds in the Environment (RECETOX) , Brno , Czech Republic.
245    10
$a Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes / $c T. Pavlová, F. Zlámal, Z. Šplíchal, J. Tomandl, Z. Hodická, P. Ventruba, J. Bienertová-Vašků,
520    9_
$a OBJECTIVES: The aim of the study is to investigate differences in visfatin concentrations between mothers with term and preterm birth (PTB) and between mothers who delivered within seven days and after more than seven days following admission for PTB/preterm premature rupture of membranes (PPROMs). METHODS: Maternal peripheral blood and cord blood were collected from 56 mothers with PTB (31 with PPROM) and 71 mothers with term delivery (three with PPROM). RESULTS: Maternal visfatin concentration was significantly higher for given gestational age in PTBs compared to term deliveries (p = .021) and also in mothers who delivered within seven days after admission for PTB or PPROM, compared to those who delivered after more than seven days (p = .027; p = .039). Cord blood visfatin concentration was found to be decreased in preterm compared to term infants (p = .007). CONCLUSIONS: Visfatin in both maternal and fetal circulation may play an important role in the pathogenesis of PTB/PPROM and could be used to distinguish between women who will deliver in a short period of time after clinical presentation of PTB/PPROM and those who deliver later. Nevertheless, additional research is necessary in order to identify its direct involvement in PTB/PPROM.
650    _2
$a dospělí $7 D000328
650    _2
$a studie případů a kontrol $7 D016022
650    _2
$a cytokiny $x krev $x genetika $7 D016207
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a fetální krev $x chemie $7 D005312
650    _2
$a předčasný odtok plodové vody $x krev $x genetika $7 D005322
650    _2
$a genotyp $7 D005838
650    _2
$a lidé $7 D006801
650    _2
$a nikotinamidfosforibosyltransferasa $x krev $x genetika $7 D054409
650    _2
$a jednonukleotidový polymorfismus $7 D020641
650    _2
$a těhotenství $7 D011247
650    _2
$a předčasný porod $x krev $x genetika $7 D047928
655    _2
$a časopisecké články $7 D016428
700    1_
$a Zlámal, Filip $u a Department of Pathological Physiology, Faculty of Medicine , Masaryk University , Brno , Czech Republic. b Research Centre for the Toxic Compounds in the Environment (RECETOX) , Brno , Czech Republic.
700    1_
$a Šplíchal, Zbyněk $u a Department of Pathological Physiology, Faculty of Medicine , Masaryk University , Brno , Czech Republic.
700    1_
$a Tomandl, Josef $u c Department of Biochemistry, Faculty of Medicine , Masaryk University , Brno , Czech Republic.
700    1_
$a Hodická, Zuzana $u d Department of Obstetrics and Gynaecology , University Hospital Brno , Brno , Czech Republic.
700    1_
$a Ventruba, Pavel $u d Department of Obstetrics and Gynaecology , University Hospital Brno , Brno , Czech Republic.
700    1_
$a Bienertová-Vašků, Julie $u a Department of Pathological Physiology, Faculty of Medicine , Masaryk University , Brno , Czech Republic. b Research Centre for the Toxic Compounds in the Environment (RECETOX) , Brno , Czech Republic.
773    0_
$w MED00007048 $t The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians $x 1476-4954 $g Roč. 31, č. 14 (2018), s. 1811-1818
856    41
$u https://pubmed.ncbi.nlm.nih.gov/28482725 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20190107 $b ABA008
991    __
$a 20190121121004 $b ABA008
999    __
$a ok $b bmc $g 1365151 $s 1039385
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 31 $c 14 $d 1811-1818 $e 20170525 $i 1476-4954 $m Journal of maternal-fetal & neonatal medicine $n J Matern Fetal Neonatal Med $x MED00007048
LZP    __
$a Pubmed-20190107

Find record

Citation metrics

Archiving options