Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Value of a comprehensive geriatric assessment for predicting one-year outcomes in patients undergoing transcatheter aortic valve implantation: results from the CGA-TAVI multicentre registry

MS. van Mourik, N. van der Velde, G. Mannarino, MP. Thibodeau, JB. Masson, G. Santoro, J. Baan, S. Jansen, J. Kurucova, M. Thoenes, C. Deutsch, AW. Schoenenberger, A. Ungar, P. Bramlage, MM. Vis,

. 2019 ; 16 (6) : 468-477. [pub] -

Jazyk angličtina Země Tchaj-wan

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc19035950

Background: In a three-month report from the CGA-TAVI registry, we found the Multidimensional Prognostic Index (MPI) and Short Physical Performance Battery (SPPB) to be of value for predicting short-term outcomes in elderly patients undergoing transcatheter aortic valve implantation (TAVI). In the present analysis, we examined the association of these tools with outcomes up to one year post-TAVI. Methods: CGA-TAVI is an international, observational registry of geriatric patients undergoing TAVI. Patients were assessed using the MPI and SPPB. Efficacy of baseline values and any postoperative change for predicting outcome were established using logistic regression. Kaplan-Meier analysis was carried out for each comprehensive geriatric assessment tool, with survival stratified by risk category. Results: One year after TAVI, 14.1% of patients deceased, while 17.4% met the combined endpoint of death and/or non-fatal stroke, and 37.7% the combined endpoint of death and/or hospitalisation and/or non-fatal stroke. A high-risk MPI score was associated with an increased risk of all-cause mortality (aOR = 36.13, 95% CI: 2.77-470.78, P = 0.006) and death and/or non-fatal stroke (aOR = 10.10, 95% CI: 1.48-68.75, P = 0.018). No significant associations were found between a high-risk SPPB score and mortality or two main combined endpoints. In contrast to a worsening SPPB, an aggravating MPI score at three months post-TAVI was associated with an increased risk of death and/or non-fatal stoke at one year (aOR = 95.16, 95% CI: 3.41-2657.01). Conclusions: The MPI showed value for predicting the likelihood of death and a combination of death and/or non-fatal stroke by one year after TAVI in elderly patients.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19035950
003      
CZ-PrNML
005      
20191014105845.0
007      
ta
008      
191007s2019 ch f 000 0|eng||
009      
AR
024    7_
$a 10.11909/j.issn.1671-5411.2019.06.001 $2 doi
035    __
$a (PubMed)31308839
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a ch
100    1_
$a van Mourik, Martijn S $u Department of Cardiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
245    10
$a Value of a comprehensive geriatric assessment for predicting one-year outcomes in patients undergoing transcatheter aortic valve implantation: results from the CGA-TAVI multicentre registry / $c MS. van Mourik, N. van der Velde, G. Mannarino, MP. Thibodeau, JB. Masson, G. Santoro, J. Baan, S. Jansen, J. Kurucova, M. Thoenes, C. Deutsch, AW. Schoenenberger, A. Ungar, P. Bramlage, MM. Vis,
520    9_
$a Background: In a three-month report from the CGA-TAVI registry, we found the Multidimensional Prognostic Index (MPI) and Short Physical Performance Battery (SPPB) to be of value for predicting short-term outcomes in elderly patients undergoing transcatheter aortic valve implantation (TAVI). In the present analysis, we examined the association of these tools with outcomes up to one year post-TAVI. Methods: CGA-TAVI is an international, observational registry of geriatric patients undergoing TAVI. Patients were assessed using the MPI and SPPB. Efficacy of baseline values and any postoperative change for predicting outcome were established using logistic regression. Kaplan-Meier analysis was carried out for each comprehensive geriatric assessment tool, with survival stratified by risk category. Results: One year after TAVI, 14.1% of patients deceased, while 17.4% met the combined endpoint of death and/or non-fatal stroke, and 37.7% the combined endpoint of death and/or hospitalisation and/or non-fatal stroke. A high-risk MPI score was associated with an increased risk of all-cause mortality (aOR = 36.13, 95% CI: 2.77-470.78, P = 0.006) and death and/or non-fatal stroke (aOR = 10.10, 95% CI: 1.48-68.75, P = 0.018). No significant associations were found between a high-risk SPPB score and mortality or two main combined endpoints. In contrast to a worsening SPPB, an aggravating MPI score at three months post-TAVI was associated with an increased risk of death and/or non-fatal stoke at one year (aOR = 95.16, 95% CI: 3.41-2657.01). Conclusions: The MPI showed value for predicting the likelihood of death and a combination of death and/or non-fatal stroke by one year after TAVI in elderly patients.
655    _2
$a časopisecké články $7 D016428
700    1_
$a van der Velde, Nathalie $u Department of Internal Medicine, Section of Geriatric Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
700    1_
$a Mannarino, Giulio $u Geriatric Intensive Care Unit, Department of Geriatrics and Medicine, Careggi Hospital and University of Florence, Italy.
700    1_
$a Thibodeau, Marie-Pierre $u Centre Hospitalier de l'Université de Montréal, Montréal, Canada.
700    1_
$a Masson, Jean-Bernard $u Centre Hospitalier de l'Université de Montréal, Montréal, Canada.
700    1_
$a Santoro, Gennaro $u Geriatric Intensive Care Unit, Department of Geriatrics and Medicine, Careggi Hospital and University of Florence, Italy.
700    1_
$a Baan, Jan $u Department of Cardiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
700    1_
$a Jansen, Sofie $u Department of Internal Medicine, Section of Geriatric Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
700    1_
$a Kurucova, Jana $u Edwards Lifesciences, Prague, Czech Republic.
700    1_
$a Thoenes, Martin $u Edwards Lifesciences, Nyon, Switzerland.
700    1_
$a Deutsch, Cornelia $u Institute for Pharmacology und Preventive Medicine, Cloppenburg, Germany.
700    1_
$a Schoenenberger, Andreas W $u Department of Geriatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland.
700    1_
$a Ungar, Andrea $u Geriatric Intensive Care Unit, Department of Geriatrics and Medicine, Careggi Hospital and University of Florence, Italy.
700    1_
$a Bramlage, Peter $u Institute for Pharmacology und Preventive Medicine, Cloppenburg, Germany.
700    1_
$a Vis, M Marije $u Department of Cardiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
773    0_
$w MED00194313 $t Journal of geriatric cardiology : JGC $x 1671-5411 $g Roč. 16, č. 6 (2019), s. 468-477
856    41
$u https://pubmed.ncbi.nlm.nih.gov/31308839 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20191007 $b ABA008
991    __
$a 20191014110309 $b ABA008
999    __
$a ind $b bmc $g 1452610 $s 1074500
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2019 $b 16 $c 6 $d 468-477 $e - $i 1671-5411 $m Journal of geriatric cardiology $n J Geriatr Cardiol $x MED00194313
LZP    __
$a Pubmed-20191007

Najít záznam

Citační ukazatele

Možnosti archivace