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Interplay among IncA and blaKPC-Carrying Plasmids in Citrobacter freundii

I. Bitar, M. Caltagirone, L. Villa, V. Mattioni Marchetti, E. Nucleo, M. Sarti, R. Migliavacca, A. Carattoli,

. 2019 ; 63 (5) : . [pub] 20190425

Language English Country United States

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc20006536
E-resources Online Full text

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Links

PubMed 30858205
DOI 10.1128/aac.02609-18
Knihovny.cz E-resources

We report two KPC-producing Citrobacter freundii isolates from unrelated patients. In one case, blaKPC-2 was harbored on a novel variant of a Tn4401 transposon of an IncN plasmid conjugated together with a coresident IncA plasmid, whereas in the other one, blaKPC-3 was on a Tn4401a transposon located on an IncX3-IncA self-conjugative plasmid fusion. The interplay among plasmids carrying blaKPC and the coresident IncA plasmids offers new information on plasmids coresident within clinically relevant enterobacteria.

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