-
Je něco špatně v tomto záznamu ?
Genetic characterizations of Cryptosporidium spp. from pet rodents indicate high zoonotic potential of pathogens from chinchillas
J. Chen, W. Wang, Y. Lin, L. Sun, N. Li, Y. Guo, M. Kvac, U. Ryan, Y. Feng, L. Xiao
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články
PubMed Central od 2015
Open Access Digital Library od 2015-12-01
Elsevier Open Access Journals od 2015-12-01
ROAD: Directory of Open Access Scholarly Resources od 2015
Odkazy
PubMed
34113708
DOI
10.1016/j.onehlt.2021.100269
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
Cryptosporidium spp. are common protozoan pathogens in mammals. With pet rodents being integrated into modern life, the potential roles of them in transmitting parasites to humans need assessments. In the present study, we examined the occurrence of Cryptosporidium spp. in pet rodents in Guangdong, south China. A total of 697 fecal samples were collected from 11 species of rodents in seven pet shops, one pet market and one farm. Cryptosporidium spp. were identified by PCR analysis of the small subunit rRNA gene. An overall infection rate of 36.9% (257/697) was obtained, with infection rates varying from 9.3% in chinchillas, 52.3% in guinea pigs, 57.1% in squirrels, to 68.4% in cricetid animals. Nine Cryptosporidium species and genotypes were identified, including C. wrairi (in 129 guinea pigs), C. andersoni (in 34 hamsters), C. homai (in 32 guinea pigs), Cryptosporidium hamster genotype (in 30 hamsters), C. ubiquitum (in 24 chinchillas and squirrels), C. parvum (in 2 chinchillas), Cryptosporidium ferret genotype (in 2 chipmunks), C. muris (in 1 hamster and 1 guinea pig), and Cryptosporidium chipmunk genotype V (in 1 chinchilla and 1 chipmunk). Sequence analysis of the 60 kDa glycoprotein gene identified three subtype families of C. ubiquitum, including family XIId in 15 chinchillas, XIIa in 5 chinchillas, and a new subtype family (XIIi) in 1 squirrel. The identification of C. parvum and C. ubiquitum in pet rodents suggests that these animals, especially chinchillas, could serve as reservoirs of human-pathogenic Cryptosporidium spp. Hygiene should be practiced in the rear and care of these animals, and One Health measures should be developed to reduce the occurrence of zoonotic Cryptosporidium infections due to contact with pet rodents.
Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642 China
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21017694
- 003
- CZ-PrNML
- 005
- 20210729103940.0
- 007
- ta
- 008
- 210726s2021 ne f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.onehlt.2021.100269 $2 doi
- 035 __
- $a (PubMed)34113708
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a ne
- 100 1_
- $a Chen, Jia $u Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China $u Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
- 245 10
- $a Genetic characterizations of Cryptosporidium spp. from pet rodents indicate high zoonotic potential of pathogens from chinchillas / $c J. Chen, W. Wang, Y. Lin, L. Sun, N. Li, Y. Guo, M. Kvac, U. Ryan, Y. Feng, L. Xiao
- 520 9_
- $a Cryptosporidium spp. are common protozoan pathogens in mammals. With pet rodents being integrated into modern life, the potential roles of them in transmitting parasites to humans need assessments. In the present study, we examined the occurrence of Cryptosporidium spp. in pet rodents in Guangdong, south China. A total of 697 fecal samples were collected from 11 species of rodents in seven pet shops, one pet market and one farm. Cryptosporidium spp. were identified by PCR analysis of the small subunit rRNA gene. An overall infection rate of 36.9% (257/697) was obtained, with infection rates varying from 9.3% in chinchillas, 52.3% in guinea pigs, 57.1% in squirrels, to 68.4% in cricetid animals. Nine Cryptosporidium species and genotypes were identified, including C. wrairi (in 129 guinea pigs), C. andersoni (in 34 hamsters), C. homai (in 32 guinea pigs), Cryptosporidium hamster genotype (in 30 hamsters), C. ubiquitum (in 24 chinchillas and squirrels), C. parvum (in 2 chinchillas), Cryptosporidium ferret genotype (in 2 chipmunks), C. muris (in 1 hamster and 1 guinea pig), and Cryptosporidium chipmunk genotype V (in 1 chinchilla and 1 chipmunk). Sequence analysis of the 60 kDa glycoprotein gene identified three subtype families of C. ubiquitum, including family XIId in 15 chinchillas, XIIa in 5 chinchillas, and a new subtype family (XIIi) in 1 squirrel. The identification of C. parvum and C. ubiquitum in pet rodents suggests that these animals, especially chinchillas, could serve as reservoirs of human-pathogenic Cryptosporidium spp. Hygiene should be practiced in the rear and care of these animals, and One Health measures should be developed to reduce the occurrence of zoonotic Cryptosporidium infections due to contact with pet rodents.
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Wang, Weijian $u Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China $u Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
- 700 1_
- $a Lin, Yu $u Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China $u Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
- 700 1_
- $a Sun, Lianbei $u Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China $u Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
- 700 1_
- $a Li, Na $u Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China $u Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
- 700 1_
- $a Guo, Yaqiong $u Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China $u Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
- 700 1_
- $a Kvac, Martin $u Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Branisovska 31, 37005 Ceske Budejovice, Czech Republic
- 700 1_
- $a Ryan, Una $u Harry Butler Institute, Murdoch University, Perth, Australia
- 700 1_
- $a Feng, Yaoyu $u Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China $u Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
- 700 1_
- $a Xiao, Lihua $u Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China $u Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
- 773 0_
- $w MED00207617 $t One health (Amsterdam, Netherlands) $x 2352-7714 $g Roč. 13, č. - (2021), s. 100269
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/34113708 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y - $z 0
- 990 __
- $a 20210726 $b ABA008
- 991 __
- $a 20210729103939 $b ABA008
- 999 __
- $a ind $b bmc $g 1676390 $s 1138136
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2021 $b 13 $c - $d 100269 $e 20210524 $i 2352-7714 $m One health $n One Health $x MED00207617
- LZP __
- $a Pubmed-20210726