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PrEP Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future
D. Gokengin, D. Bursa, A. Skrzat-Klapaczynska, I. Alexiev, E. Arsikj, T. Balayan, J. Begovac, A. Cicic, G. Dragovic, A. Harxhi, K. Aimla, B. Lakatos, R. Matulionyte, V. Mulabdic, C. Oprea, A. Papadopoulos, N. Rukhadze, D. Sedlacek, L. Sojak, J....
Status neindexováno Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články
Free Medical Journals od 2013
PubMed Central od 2013
Europe PubMed Central od 2013
ProQuest Central od 2013-03-01
Open Access Digital Library od 2013-01-01
Open Access Digital Library od 2013-01-01
ROAD: Directory of Open Access Scholarly Resources od 2013
Odkazy
PubMed
36679967
DOI
10.3390/vaccines11010122
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
With no expected vaccine for HIV in the near future, we aimed to define the current situation and challenges for pre- and post-exposure prophylaxis (PrEP and PEP) in Central and Eastern Europe (CEE). The Euroguidelines CEE Network Group members were invited to respond to a 27-item survey including questions on PrEP (response rate 91.6%). PrEP was licensed in 68.2%; 95 centers offered PrEP and the estimated number on PrEP was around 9000. It was available in daily (40.1%), on-demand (13.3%), or both forms (33.3%). The access rate was <1−80%. Three major barriers for access were lack of knowledge/awareness among people who are in need (59.1%), not being reimbursed (50.0%), and low perception of HIV risk (45.5%). Non-occupational PEP was available in 86.4% and was recommended in the guidelines in 54.5%. It was fully reimbursed in 36.4%, only for accidental exposures in 40.9%, and was not reimbursed in 22.72%. Occupational PEP was available in 95.5% and was reimbursed fully. Although PrEP scale-up in the region has gained momentum, a huge gap exists between those who are in need of and those who can access PrEP. Prompt action is required to address the urgent need for PrEP scale-up in the CEE region.
Astar Medical Center 79054 Lviv Ukraine
Department of Infectious Diseases School of Medicine University of Zagreb 10000 Zagreb Croatia
Department of Infectious Diseases Tartu University Hospital 50406 Tartu Estonia
Department of Infectious Diseases University Medical Center Ljubljana 1525 Ljubljana Slovenia
Department of Virology National Center of Infectious and Parasitic Diseases 1504 Sofia Bulgaria
HIV AIDS Research and Practice Center Ege University Izmir 35100 Türkiye
HIV Center University Hospital Charles University 11000 Pilsen Czech Republic
Infectious Diseases AIDS and Clinical Immunology Research Center 0160 Tbilisi Georgia
Internal Medicine Department Erasmus MC 2040 3000 Rotterdam The Netherlands
National Center for Disease Control and Prevention Yerevan 0025 Armenia
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