-
Je něco špatně v tomto záznamu ?
PrEP Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future
D. Gokengin, D. Bursa, A. Skrzat-Klapaczynska, I. Alexiev, E. Arsikj, T. Balayan, J. Begovac, A. Cicic, G. Dragovic, A. Harxhi, K. Aimla, B. Lakatos, R. Matulionyte, V. Mulabdic, C. Oprea, A. Papadopoulos, N. Rukhadze, D. Sedlacek, L. Sojak, J....
Status neindexováno Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články
Free Medical Journals od 2013
PubMed Central od 2013
Europe PubMed Central od 2013
ProQuest Central od 2013-03-01
Open Access Digital Library od 2013-01-01
Open Access Digital Library od 2013-01-01
ROAD: Directory of Open Access Scholarly Resources od 2013
Odkazy
PubMed
36679967
DOI
10.3390/vaccines11010122
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
With no expected vaccine for HIV in the near future, we aimed to define the current situation and challenges for pre- and post-exposure prophylaxis (PrEP and PEP) in Central and Eastern Europe (CEE). The Euroguidelines CEE Network Group members were invited to respond to a 27-item survey including questions on PrEP (response rate 91.6%). PrEP was licensed in 68.2%; 95 centers offered PrEP and the estimated number on PrEP was around 9000. It was available in daily (40.1%), on-demand (13.3%), or both forms (33.3%). The access rate was <1−80%. Three major barriers for access were lack of knowledge/awareness among people who are in need (59.1%), not being reimbursed (50.0%), and low perception of HIV risk (45.5%). Non-occupational PEP was available in 86.4% and was recommended in the guidelines in 54.5%. It was fully reimbursed in 36.4%, only for accidental exposures in 40.9%, and was not reimbursed in 22.72%. Occupational PEP was available in 95.5% and was reimbursed fully. Although PrEP scale-up in the region has gained momentum, a huge gap exists between those who are in need of and those who can access PrEP. Prompt action is required to address the urgent need for PrEP scale-up in the CEE region.
Astar Medical Center 79054 Lviv Ukraine
Department of Infectious Diseases School of Medicine University of Zagreb 10000 Zagreb Croatia
Department of Infectious Diseases Tartu University Hospital 50406 Tartu Estonia
Department of Infectious Diseases University Medical Center Ljubljana 1525 Ljubljana Slovenia
Department of Virology National Center of Infectious and Parasitic Diseases 1504 Sofia Bulgaria
HIV AIDS Research and Practice Center Ege University Izmir 35100 Türkiye
HIV Center University Hospital Charles University 11000 Pilsen Czech Republic
Infectious Diseases AIDS and Clinical Immunology Research Center 0160 Tbilisi Georgia
Internal Medicine Department Erasmus MC 2040 3000 Rotterdam The Netherlands
National Center for Disease Control and Prevention Yerevan 0025 Armenia
- 000
- 00000naa a2200000 a 4500
- 001
- bmc23003235
- 003
- CZ-PrNML
- 005
- 20230421100127.0
- 007
- ta
- 008
- 230413s2023 sz f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3390/vaccines11010122 $2 doi
- 035 __
- $a (PubMed)36679967
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a sz
- 100 1_
- $a Gokengin, Deniz $u Department of Infectious Diseases and Clinical Microbiology, Medical Faculty, Ege University, Izmir 35100, Türkiye $u HIV/AIDS Research and Practice Center, Ege University, Izmir 35100, Türkiye $1 https://orcid.org/0000000307042302
- 245 10
- $a PrEP Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future / $c D. Gokengin, D. Bursa, A. Skrzat-Klapaczynska, I. Alexiev, E. Arsikj, T. Balayan, J. Begovac, A. Cicic, G. Dragovic, A. Harxhi, K. Aimla, B. Lakatos, R. Matulionyte, V. Mulabdic, C. Oprea, A. Papadopoulos, N. Rukhadze, D. Sedlacek, L. Sojak, J. Tomazic, A. Vassilenko, M. Vasylyev, A. Verhaz, N. Yancheva, O. Yurin, J. Kowalska, Euroguidelines in Central and Eastern Europe (ECEE) Network Group
- 520 9_
- $a With no expected vaccine for HIV in the near future, we aimed to define the current situation and challenges for pre- and post-exposure prophylaxis (PrEP and PEP) in Central and Eastern Europe (CEE). The Euroguidelines CEE Network Group members were invited to respond to a 27-item survey including questions on PrEP (response rate 91.6%). PrEP was licensed in 68.2%; 95 centers offered PrEP and the estimated number on PrEP was around 9000. It was available in daily (40.1%), on-demand (13.3%), or both forms (33.3%). The access rate was <1−80%. Three major barriers for access were lack of knowledge/awareness among people who are in need (59.1%), not being reimbursed (50.0%), and low perception of HIV risk (45.5%). Non-occupational PEP was available in 86.4% and was recommended in the guidelines in 54.5%. It was fully reimbursed in 36.4%, only for accidental exposures in 40.9%, and was not reimbursed in 22.72%. Occupational PEP was available in 95.5% and was reimbursed fully. Although PrEP scale-up in the region has gained momentum, a huge gap exists between those who are in need of and those who can access PrEP. Prompt action is required to address the urgent need for PrEP scale-up in the CEE region.
- 590 __
- $a NEINDEXOVÁNO
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Bursa, Dominik $u Department of Adults' Infectious Diseases, Hospital for Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland
- 700 1_
- $a Skrzat-Klapaczynska, Agata $u Department of Adults' Infectious Diseases, Hospital for Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland
- 700 1_
- $a Alexiev, Ivailo $u Department of Virology, National Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria $1 https://orcid.org/0000000231861124
- 700 1_
- $a Arsikj, Elena $u University Clinic for Infectious Diseases and Febrile Conditions Skopje, Faculty of Medicine Skopje, Ss.Cyril and Methodius University, 1010 Skopje, North Macedonia $1 https://orcid.org/0000000257845405
- 700 1_
- $a Balayan, Tatevik $u National Center for Disease Control and Prevention, Yerevan 0025, Armenia
- 700 1_
- $a Begovac, Josip $u Department of Infectious Diseases, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia $1 https://orcid.org/0000000326414327
- 700 1_
- $a Cicic, Alma $u Center for Communicable Disease Control and Prevention, Institute for Public Health of Montenegro, 81000 Podgorica, Montenegro
- 700 1_
- $a Dragovic, Gordana $u Department of Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine, University of Belgrade, 11000 Belgrade, Serbia
- 700 1_
- $a Harxhi, Arjan $u Department of Infectious Disease, Faculty of Medicine, University Hospital Center of Tirana, 1001 Tirana, Albania
- 700 1_
- $a Aimla, Kerstin $u Department of Infectious Diseases, Tartu University Hospital, 50406 Tartu, Estonia
- 700 1_
- $a Lakatos, Botond $u Department of HIV and Tropical Diseases, South Pest Central Hospital, National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary
- 700 1_
- $a Matulionyte, Raimonda $u Department of Infectious Diseases and Dermatovenerology, Vilnius University Hospital Santaros Klinikos, Vilnius University, LT-08410 Vilnius, Lithuania
- 700 1_
- $a Mulabdic, Velida $u Clinic for Infectious Diseases, Clinical Center University of Sarajevo, 71000 Sarajevo, Bosnia and Herzegovina
- 700 1_
- $a Oprea, Cristiana $u Victor Babes Hospital for Infectious and Tropical Diseases, Carol Davila University of Medicine and Pharmacy, 030303 Bucharest, Romania
- 700 1_
- $a Papadopoulos, Antonios $u 4th Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, University General Hospital "ATTIKON", 12462 Athens, Greece $1 https://orcid.org/0000000347352620
- 700 1_
- $a Rukhadze, Nino $u Infectious Diseases, AIDS & Clinical Immunology Research Center, 0160 Tbilisi, Georgia $1 https://orcid.org/000000034055086X
- 700 1_
- $a Sedlacek, Dalibor $u HIV Center University Hospital, Charles University, 11000 Pilsen, Czech Republic $1 https://orcid.org/0000000347116679 $7 nlk20040152782
- 700 1_
- $a Sojak, Lubomir $u Center for Treatment of HIV/AIDS Patients, Department of Infectology and Geographical Medicine, Academic L. Derer's University Hospital, 2412 Bratislava, Slovakia $1 https://orcid.org/0000000187450845
- 700 1_
- $a Tomazic, Janez $u Department of Infectious Diseases, University Medical Center Ljubljana, 1525 Ljubljana, Slovenia
- 700 1_
- $a Vassilenko, Anna $u Global Fund Grant Management Department, Republican Scientific and Practical Center of Medical Technologies, Informatization, Management and Economics of Public Health (RNPT MT), 220013 Minsk, Belarus $1 https://orcid.org/0000000319072322
- 700 1_
- $a Vasylyev, Marta $u Astar Medical Center, 79054 Lviv, Ukraine $u Internal Medicine Department, Erasmus MC, 2040 3000 Rotterdam, The Netherlands
- 700 1_
- $a Verhaz, Antonija $u Clinic for Infectious Diseases, University Clinical Center of the Republic of Srpska, 78000 Banja Luka, Bosnia and Herzegovina
- 700 1_
- $a Yancheva, Nina $u Department for AIDS, Specialized Hospital for Active Treatment of Infectious and Parasitic Diseases-Sofia, Medical University Sofia, 1431 Sofia, Bulgaria
- 700 1_
- $a Yurin, Oleg $u Department of AIDS, Epidemiology and Prevention, Central Research Institute of Epidemiology, Federal AIDS Centre, 111123 Moscow, Russia $1 https://orcid.org/0000000319307486
- 700 1_
- $a Kowalska, Justyna $u Department of Adults' Infectious Diseases, Hospital for Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland $u HIV Out-Patient Clinic, Hospital for Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland
- 710 2_
- $a Euroguidelines in Central and Eastern Europe (ECEE) Network Group
- 773 0_
- $w MED00200686 $t Vaccines $x 2076-393X $g Roč. 11, č. 1 (2023)
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/36679967 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20230413 $b ABA008
- 991 __
- $a 20230421100119 $b ABA008
- 999 __
- $a ok $b bmc $g 1922831 $s 1189442
- BAS __
- $a 3
- BAS __
- $a PreBMC-PubMed-not-MEDLINE
- BMC __
- $a 2023 $b 11 $c 1 $e 20230104 $i 2076-393X $m Vaccines $n Vaccines (Basel) $x MED00200686
- LZP __
- $a Pubmed-20230413