• Something wrong with this record ?

Telomerase RNA in Hymenoptera (Insecta) switched to plant/ciliate-like biogenesis

P. Fajkus, M. Adámik, ADL. Nelson, AM. Kilar, M. Franek, M. Bubeník, RČ. Frydrychová, A. Votavová, E. Sýkorová, J. Fajkus, V. Peška

. 2023 ; 51 (1) : 420-433. [pub] 2023Jan11

Language English Country England, Great Britain

Document type Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.

Persistent link   https://www.medvik.cz/link/bmc23004621

In contrast to the catalytic subunit of telomerase, its RNA subunit (TR) is highly divergent in size, sequence and biogenesis pathways across eukaryotes. Current views on TR evolution assume a common origin of TRs transcribed with RNA polymerase II in Opisthokonta (the supergroup including Animalia and Fungi) and Trypanosomida on one hand, and TRs transcribed with RNA polymerase III under the control of type 3 promoter, found in TSAR and Archaeplastida supergroups (including e.g. ciliates and Viridiplantae taxa, respectively). Here, we focus on unknown TRs in one of the largest Animalia order - Hymenoptera (Arthropoda) with more than 300 available representative genomes. Using a combination of bioinformatic and experimental approaches, we identify their TRs. In contrast to the presumed type of TRs (H/ACA box snoRNAs transcribed with RNA Polymerase II) corresponding to their phylogenetic position, we find here short TRs of the snRNA type, likely transcribed with RNA polymerase III under the control of the type 3 promoter. The newly described insect TRs thus question the hitherto assumed monophyletic origin of TRs across Animalia and point to an evolutionary switch in TR type and biogenesis that was associated with the divergence of Arthropods.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc23004621
003      
CZ-PrNML
005      
20230425171628.0
007      
ta
008      
230418s2023 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1093/nar/gkac1202 $2 doi
035    __
$a (PubMed)36546771
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Fajkus, Petr $u Department of Cell Biology and Radiobiology, Institute of Biophysics of the Czech Academy of Sciences, Brno CZ-61265, Czech Republic $u Mendel Centre for Plant Genomics and Proteomics, CEITEC Masaryk University, Brno CZ-62500, Czech Republic
245    10
$a Telomerase RNA in Hymenoptera (Insecta) switched to plant/ciliate-like biogenesis / $c P. Fajkus, M. Adámik, ADL. Nelson, AM. Kilar, M. Franek, M. Bubeník, RČ. Frydrychová, A. Votavová, E. Sýkorová, J. Fajkus, V. Peška
520    9_
$a In contrast to the catalytic subunit of telomerase, its RNA subunit (TR) is highly divergent in size, sequence and biogenesis pathways across eukaryotes. Current views on TR evolution assume a common origin of TRs transcribed with RNA polymerase II in Opisthokonta (the supergroup including Animalia and Fungi) and Trypanosomida on one hand, and TRs transcribed with RNA polymerase III under the control of type 3 promoter, found in TSAR and Archaeplastida supergroups (including e.g. ciliates and Viridiplantae taxa, respectively). Here, we focus on unknown TRs in one of the largest Animalia order - Hymenoptera (Arthropoda) with more than 300 available representative genomes. Using a combination of bioinformatic and experimental approaches, we identify their TRs. In contrast to the presumed type of TRs (H/ACA box snoRNAs transcribed with RNA Polymerase II) corresponding to their phylogenetic position, we find here short TRs of the snRNA type, likely transcribed with RNA polymerase III under the control of the type 3 promoter. The newly described insect TRs thus question the hitherto assumed monophyletic origin of TRs across Animalia and point to an evolutionary switch in TR type and biogenesis that was associated with the divergence of Arthropods.
650    _2
$a zvířata $7 D000818
650    12
$a telomerasa $x genetika $x metabolismus $7 D019098
650    12
$a Hymenoptera $x genetika $7 D006927
650    _2
$a fylogeneze $7 D010802
650    _2
$a RNA-polymerasa II $x genetika $x metabolismus $7 D012319
650    _2
$a RNA-polymerasa III $x genetika $x metabolismus $7 D012320
650    _2
$a konformace nukleové kyseliny $7 D009690
650    _2
$a RNA $x genetika $7 D012313
650    _2
$a rostliny $x genetika $7 D010944
650    _2
$a Eukaryota $x genetika $7 D056890
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
655    _2
$a Research Support, U.S. Gov't, Non-P.H.S. $7 D013486
700    1_
$a Adámik, Matej $u Department of Cell Biology and Radiobiology, Institute of Biophysics of the Czech Academy of Sciences, Brno CZ-61265, Czech Republic
700    1_
$a Nelson, Andrew D L $u The Boyce Thompson Institute, Cornell University, 533 Tower Road, Ithaca, NY 14850, USA
700    1_
$a Kilar, Agata M $u Mendel Centre for Plant Genomics and Proteomics, CEITEC Masaryk University, Brno CZ-62500, Czech Republic $u Laboratory of Functional Genomics and Proteomics, NCBR, Faculty of Science, Masaryk University, Brno CZ-61137, Czech Republic
700    1_
$a Franek, Michal $u Mendel Centre for Plant Genomics and Proteomics, CEITEC Masaryk University, Brno CZ-62500, Czech Republic $1 https://orcid.org/0000000296271301
700    1_
$a Bubeník, Michal $u Laboratory of Functional Genomics and Proteomics, NCBR, Faculty of Science, Masaryk University, Brno CZ-61137, Czech Republic
700    1_
$a Frydrychová, Radmila Čapková $u Biology Centre of the Czech Academy of Sciences, Institute of Entomology, České Budějovice CZ-37005, Czech Republic
700    1_
$a Votavová, Alena $u Agricultural Research, Ltd., Troubsko, CZ-664 41, Czech Republic
700    1_
$a Sýkorová, Eva $u Department of Cell Biology and Radiobiology, Institute of Biophysics of the Czech Academy of Sciences, Brno CZ-61265, Czech Republic $1 https://orcid.org/000000024048034X
700    1_
$a Fajkus, Jiří $u Department of Cell Biology and Radiobiology, Institute of Biophysics of the Czech Academy of Sciences, Brno CZ-61265, Czech Republic $u Mendel Centre for Plant Genomics and Proteomics, CEITEC Masaryk University, Brno CZ-62500, Czech Republic $u Laboratory of Functional Genomics and Proteomics, NCBR, Faculty of Science, Masaryk University, Brno CZ-61137, Czech Republic $1 https://orcid.org/0000000231121716 $7 xx0062744
700    1_
$a Peška, Vratislav $u Department of Cell Biology and Radiobiology, Institute of Biophysics of the Czech Academy of Sciences, Brno CZ-61265, Czech Republic $1 https://orcid.org/0000000205262988 $7 mub20211130857
773    0_
$w MED00003554 $t Nucleic acids research $x 1362-4962 $g Roč. 51, č. 1 (2023), s. 420-433
856    41
$u https://pubmed.ncbi.nlm.nih.gov/36546771 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20230418 $b ABA008
991    __
$a 20230425171624 $b ABA008
999    __
$a ok $b bmc $g 1924985 $s 1190830
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2023 $b 51 $c 1 $d 420-433 $e 2023Jan11 $i 1362-4962 $m Nucleic acids research $n Nucleic Acids Res $x MED00003554
LZP    __
$a Pubmed-20230418

Find record

Citation metrics

Archiving options