Objectives: The objective of the evaluation was to study and determine the impact of eight weeks of aerobic training (AT) on liver enzymes and changes in hematological profile in children with leukemia. Methods: This is a semi-experimental and applied study. Statistical samples include 24 children aged 7 to 10 years that referred to hospital and were divided randomly into two control (n=12) and experimental (n=12) groups. Eight-week AT with 40 to 70 percent of heart rate reserve, three sessions per week, no exercise training program was observed in the controls during the study. We measure Liver enzymes such as Aspartate aminotransferase (AST) and alanine aminotransferase (ALT), Hemoglobin (Hb), White Blood Cells (WBC), platelets (PLT), and bilirubin. Data analysis using a paired t-test and analysis of covariance was performed with software SPSS version 20. Results: The results showed that moderate-intensity AT has a significant effect on hemoglobin and liver enzyme levels and a significant increase in Hb (p<0.05) and significant reduction the ALT and AST (p<0.05) whereas there was no significant influence on WBC, ALT, and bilirubin (p>0.05). Conclusion: AT may accelerate the oxygen supply and reduce liver damage caused by medications in children diagnosed with leukemia without having corrupting effect on PLT, bilirubin, and safety factors.

Department of Health and Exercise Rehabilitation Faculty of Health and Sport Sciences Shahid Beheshti University Tehran Iran

Hearing Disorders Research Center Hamadan University of Medical Sciences Hamadan Hamadan Iran

MAHAK Hematology Oncology Research Center MAHAK Hospital Shahid Beheshti University of Medical Sciences Tehran Iran

Physical education and sport sciences Shahid Rajaee Teacher Training University Tehran Iran

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