Efektívnost cambendazolu (Bonlam pasta) u oviec invadovaných trematódmi Dicrocoelium dentriticum
[Effectiveness of cambendazole (Bonlam paste) in sheep invaded by tramatodes (Dicrocoelium dendriticum)]
Language Slovak Country Czech Republic Media print
Document type English Abstract, Journal Article
PubMed
99862
- MeSH
- Benzimidazoles pharmacology MeSH
- Dicrocoelium drug effects MeSH
- Dicrocoeliasis drug therapy veterinary MeSH
- Cambendazole pharmacology therapeutic use MeSH
- Ointments MeSH
- Sheep Diseases drug therapy MeSH
- Sheep MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Names of Substances
- Benzimidazoles MeSH
- Cambendazole MeSH
- Ointments MeSH
Tests were performed to examine the effectiveness of a new form of cambendazole (Bonlam paste, produced by MSD, USA) in sheep, naturally invaded by the trematodes Dicrocoelium dendriticum. Single administration of 25 mg per 1 kg live weight induced a rapid decrease in the number of the excreted eggs of D. dendriticum, as counted during ovoscopic examination seven, ten, and fifteen days after administration of the chemical. The intenseffectiveness of the preparation, determined post mortem, was 95.1%. Despite this, several dicrocoelia with normal motility and with no changes on the cuticle or internal organs were found in all the animals dissected. The animals tolerated the treatment with no signs of side-effects.