Prognosticky relevantná histopatologická subtypizácia zmiesanobunkového typu Hodgkinovej choroby
[Prognostic relevance of histopathologic subtyping of mixed-cell Hodgkin's disease]
Language Slovak Country Czech Republic Media print
Document type English Abstract, Journal Article
PubMed
1628350
- MeSH
- Hodgkin Disease pathology MeSH
- Humans MeSH
- Prognosis MeSH
- Retrospective Studies MeSH
- Check Tag
- Humans MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
Mixed cellular (MC) type of Hodgkin disease was studied in a group of 92 bioptic cases diagnosed before the start of treatment. A precise histological analysis showed one subtype with lower malignancy (MC 1) and a second one with higher malignancy (MC 2). Subtype MC 1 comprised 61 cases (66 per cent), subtype MC 2 31 cases (34 per cent). Histomorphological subtyping was brought into correlation with clinical data of survival available in 65 cases (44 cases of subtype MC 1,21 cases of subtype MC 2). Different survival in both subtypes had statistical significance and prognostic relevance. Suggested subtyping is simple, based on common histological slides, without need of special additional investigation.
