Elevated endogenous nitrate synthesis associated with giardiasis
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
2351821
Knihovny.cz E-resources
- MeSH
- Adult MeSH
- Nitrites urine MeSH
- Feces parasitology MeSH
- Giardia isolation & purification MeSH
- Giardiasis drug therapy urine MeSH
- Infant MeSH
- Humans MeSH
- Metronidazole therapeutic use MeSH
- Premedication MeSH
- Pregnancy MeSH
- Animals MeSH
- Check Tag
- Adult MeSH
- Infant MeSH
- Humans MeSH
- Male MeSH
- Pregnancy MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Nitrites MeSH
- Metronidazole MeSH
Mean nitrate content in the morning urine of 117 patients with giardiasis comprises 155.3 mg/l, which exceeds about 4 fold the normal value. Maximum concentrations of 1000 mg/l were observed. Under treatment with metronidazol (Vagimid) nitrate content at first increased and then restored to normal. Endogenously synthesized nitrate with giardiasis 3-4 fold exceeds the daily nitrate intake by food and, therefore, plays an important role in total nitrate load of the patients.
