Foreign body reaction against cellophane in the athymic nude mice
Language English Country United States Media print
Document type Journal Article
PubMed
2674151
DOI
10.1002/jbm.820230810
Knihovny.cz E-resources
- MeSH
- Cellophane toxicity MeSH
- Drug Implants MeSH
- Skin pathology MeSH
- Mice, Nude MeSH
- Mice MeSH
- Foreign-Body Reaction * MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Cellophane MeSH
- Drug Implants MeSH
There are no differences in the multinucleate cell formation in normal and athymic mice after the subcutaneous implantation of a cellophane strip. The number of Ia+ epitheloid cells and multinucleate foreign body giant cells was lower and the number of epitheloid cells sharing the marker of activated macrophages (M 57) was higher in athymic compared to normal mice. The epitheloid cells of athymic and euthymic animals exhibited no difference in the expression of Mac-2 molecule. The difference of the expression of surface markers between athymic and euthymic animals does not influence the foreign body giant cell formation.
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