Occurrence of alkali-labile sites in pulse labelled DNA of Escherichia coli after the action of DNA-damaging chemicals
Language English Country United States Media print
Document type Journal Article
PubMed
3125095
DOI
10.1007/bf02877202
Knihovny.cz E-resources
- MeSH
- DNA, Bacterial biosynthesis drug effects MeSH
- Escherichia coli drug effects genetics radiation effects MeSH
- Nalidixic Acid pharmacology MeSH
- Methylnitrosourea pharmacology MeSH
- Mitomycin MeSH
- Mitomycins pharmacology MeSH
- DNA Damage MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- DNA, Bacterial MeSH
- Nalidixic Acid MeSH
- Methylnitrosourea MeSH
- Mitomycin MeSH
- Mitomycins MeSH
UV irradiated E. coli cells contain alkali labile sites in their DNA daughter chains. It is shown here that the occurrence of alkali labile sites in the newly synthesized DNA is a more common phenomenon. It occurred after treatment with two different DNA damaging chemicals, but not after treatment with nalidixic acid.
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