Comparison of some properties of normal or stimulated murine peritoneal macrophages
Language English Country Czech Republic Media print
Document type Comparative Study, Journal Article
PubMed
6714482
Knihovny.cz E-resources
- MeSH
- Ascitic Fluid MeSH
- Cell Adhesion MeSH
- Phagocytosis MeSH
- Caseins pharmacology MeSH
- Macrophages drug effects immunology physiology MeSH
- Mice, Inbred A MeSH
- Mice MeSH
- Peptide Fragments pharmacology MeSH
- Pinocytosis MeSH
- Receptors, Fc MeSH
- In Vitro Techniques MeSH
- Thioglycolates pharmacology MeSH
- Animals MeSH
- Check Tag
- Male MeSH
- Mice MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
- Names of Substances
- Caseins MeSH
- Peptide Fragments MeSH
- proteose-peptone MeSH Browser
- Receptors, Fc MeSH
- Thioglycolates MeSH
We studied phagocytic activity of murine macrophages for 2-hydroxyethylmethacrylate particles, determined the percentage of cells carrying Fc receptors for IgG1, IgG2A, IgG2B, IgM, IgA and IgE, and phagocytic activity mediated by Fc receptors, as well as pinocytic activity and adherence of normal and thioglycollate- or proteose peptone-stimulated peritoneal macrophages. A significant increase in phagocytic activity was found (the exceptions were FcR for IgG2A, IgG2B and IgM in TG-stimulated and FcR for IgA in PP-stimulated macrophages). Pinocytic activity increased two- to three-fold, adherence capacity, on the contrary, fell to one third in the TG-stimulated macrophages, whereas it remained unchanged after treatment in the PP-stimulated ones. Further evidence is provided for considerable differences in the properties of normal and stimulated peritoneal macrophages.
Fc receptor--more answers, more questions
