Selective intraarterial chemotherapy of tumors in the lingual artery territory by a new approach
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
8131174
DOI
10.1007/bf02603148
Knihovny.cz E-zdroje
- MeSH
- dospělí MeSH
- intraarteriální infuze metody MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory jazyka farmakoterapie MeSH
- nádory úst farmakoterapie MeSH
- protinádorové látky aplikace a dávkování MeSH
- ústní spodina MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- protinádorové látky MeSH
Selective intraarterial neoadjuvant chemotherapy of carcinoma in the region of the lingual artery was performed in 23 patients (bilaterally in 4 patients). The superficial temporal artery (STA) was surgically exposed and a preshaped infusion catheter was inserted. The catheter tip was maneuvered through the STA into the lingual artery under fluoroscopic guidance. Two combinations of cytostatic agents were then continually infused through the catheter for 5-9 days. Treatment response was observed in 16 patients, 9 of whom showed a complete response. The combination of cisplatin and 5-fluorouracil was found most effective. The catheter became dislocated six times among 27 catheterizations and in each instance the position could be corrected. No major complications were encountered. We conclude that selective infusion technique is safer than previously reported semiselective infusions techniques.
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