Changes in vascular pattern of chicken chorioallantois after cartilaginous extract, chondroitin sulfate and dextran sulfate treatment
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
8348985
Knihovny.cz E-resources
- MeSH
- Allantois blood supply drug effects MeSH
- Chondroitin Sulfates pharmacology MeSH
- Cartilage metabolism MeSH
- Gels MeSH
- Chick Embryo MeSH
- Proteoglycans isolation & purification pharmacology MeSH
- Dextran Sulfate pharmacology MeSH
- Gelatin MeSH
- Animals MeSH
- Check Tag
- Chick Embryo MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Chondroitin Sulfates MeSH
- Gels MeSH
- Proteoglycans MeSH
- Dextran Sulfate MeSH
- Gelatin MeSH
Cartilaginous extract, chondroitin sulfate C as well as dextran sulfate in gelatin pellets have an inhibitory effect on the development of fine capillaries, in contrast to pure gelatin pellets or pellets with sucrose. These results suggest an unspecific inhibitory effect of anionic saccharidic polymers on the development of chorioallantoic membrane vessels, because the chemical structure of dextran sulfate is (except anionic groups) different from chondroitin sulfate in the pure form or in the form of proteoglycans (in cartilaginous extract).