Troponin T levels in the cord blood of healthy term neonates
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
8789321
Knihovny.cz E-resources
- MeSH
- Blood Chemical Analysis MeSH
- Biomarkers MeSH
- Enzymes blood MeSH
- Fetal Blood chemistry MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Reference Values MeSH
- Body Weight MeSH
- Troponin T MeSH
- Troponin blood MeSH
- Age Factors MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Infant, Newborn MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Biomarkers MeSH
- Enzymes MeSH
- Troponin T MeSH
- Troponin MeSH
Troponin T (TnT) is recently being considered to be an important diagnostic marker of myocardial damage in adults, but this marker has not yet been used in neonates. The present study was designed to determine the normal level of cardiac TnT in the cord blood of healthy term neonates. Cardiac troponin T concentration in cord blood was measured in 15 healthy term neonates using commercial kit (Enzymun-Test System, Boehringer, Mannheim). TnT serum concentration was 0.05 +/- 0.04 micrograms/l in 10 of 15 babies whereas in the remaining 5 haemolysed samples its concentration was elevated (mean 0.19 +/- 0.07 micrograms/l). It is important to consider that incidental haemolysis of blood samples can mimic pathological elevation of TnT by interfering with the assay.
Dynamic changes of high-sensitivity troponin T concentration during infancy: Clinical implications