Oxidative burst of Kupffer cells: target for liver injury treatment
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
12572889
DOI
10.5507/bp.2002.003
Knihovny.cz E-resources
- MeSH
- Cytokines metabolism MeSH
- Hepatitis metabolism therapy MeSH
- Kupffer Cells metabolism physiology MeSH
- Humans MeSH
- Inflammation Mediators metabolism MeSH
- Respiratory Burst * MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Cytokines MeSH
- Inflammation Mediators MeSH
Liver injury, and frequent consequent fibrosis, is the focus of a number of research groups ranging from molecular biologists to clinicians. It encompasses many aspects and approaches. Among biochemical events the role of Kupffer cells, oxidative stress and pro-inflammatory mediators are eminent. In this review we focus on recent findings into use of natural substances for the modulation of oxidative burst as well as production of inflammatory mediators by Kupffer cells.
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