Vyuzití penetrometrie pri hodnocení sypnosti a struktury práskových látek
[Penetrometry in evaluation of flow and structure of powdered substances]
Language Czech Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
12754929
- MeSH
- Potassium Chloride MeSH
- Sodium Chloride MeSH
- Citrates MeSH
- Sodium Citrate MeSH
- Technology, Pharmaceutical * methods MeSH
- Potassium Citrate MeSH
- Powders * MeSH
- Rheology MeSH
- Particle Size MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Potassium Chloride MeSH
- Sodium Chloride MeSH
- Citrates MeSH
- Sodium Citrate MeSH
- Potassium Citrate MeSH
- Powders * MeSH
Usability of modified penetrometry is examined and significant relationships with routinely used characteristics of flowability and structure of powdered substances are searched for in size fractions of sodium chloride, potassium chloride, sodium citrate, and potassium citrate. A systematic study of interrelationships between properties made it possible to achieve sufficiently reproducible results without a necessity of consolidation. By means of factor analysis, a connection between penetrometry, bulk flow rate, and Kawakita-constant was demonstrated. For multidimensional linear regression for estimation of penetrometry, the significance of examined properties decreases in the order Kawakita-constant > loose bulk density > total porosity > bulk flow rate > mass flow rate. The most important item of knowledge gained in the study is the dependence of penetrometry on a combination of loose bulk density and Kawakita-constant.
