Vplyv chlorochinu na niektoré biochemické a hematologické parametre u pacientov s kritickou koncatinovou ischémiou
[The influence of chloroquine on some biochemical and hematological parameters in patients with critical limb ischemia]
Language Slovak Country Czech Republic Media print
Document type English Abstract, Journal Article
PubMed
15736385
- MeSH
- Leg blood supply MeSH
- Chloroquine therapeutic use MeSH
- Ischemia drug therapy metabolism MeSH
- Humans MeSH
- Check Tag
- Humans MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Names of Substances
- Chloroquine MeSH
CLI represents a major medical and social problem. The incidence is increasing and currently it was estimated 500-1000 per 1 million inhabitants. We carried out a clinical study (2000-2004) concerning monitoring of some hematological and biochemical markers during reperfusion in patients with CLI. The subject of our interest included possibilities to influence PMNL elastase by medical means and neutrophil-lymphocyte ratio which is considered a reliable and simple parameter to assess severity of clinical conditions.