Invasion of the intestinal tract by sporozoites of Eimeria coecicola and Eimeria intestinalis in naive and immune rabbits
Language English Country Germany Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Antigens, Protozoan metabolism MeSH
- Eimeria growth & development immunology pathogenicity MeSH
- Host-Parasite Interactions MeSH
- Coccidiosis immunology parasitology MeSH
- Rabbits MeSH
- Lymph Nodes parasitology MeSH
- Specific Pathogen-Free Organisms MeSH
- Intestinal Diseases, Parasitic * MeSH
- Peyer's Patches metabolism parasitology MeSH
- Antibodies, Protozoan immunology MeSH
- Spleen parasitology MeSH
- Sporozoites growth & development immunology pathology MeSH
- Intestine, Small metabolism parasitology pathology MeSH
- Animals MeSH
- Check Tag
- Rabbits MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Antigens, Protozoan MeSH
- Antibodies, Protozoan MeSH
Naive and immune specific-pathogen-free rabbits were inoculated in the duodenum with sporocysts of Eimeria coecicola or Eimeria intestinalis. Samples were taken from the following tissues: duodenum (site of penetration of sporozoites), ileum (specific target site of the endogenous development of E. intestinalis), vermiform appendix (target site of E. coecicola) and two extraintestinal sites, mesenteric lymph nodes (MLNs), and spleen. The presence of sporozoites was checked by immunohistochemistry. In rabbits primary-infected with E. coecicola, large numbers of sporozoites were detected in the duodenum, extraintestinal sites, and vermiform appendix. The abundance of sporozoites in the spleen, MLN, and appendix was significantly reduced in the immune rabbits, and the migration seemed impeded. In the rabbits infected with E. intestinalis, sporozoites were absent in the spleen and MLN, indicating that the route of migration is different from that of E. coecicola. The number of sporozoites in the crypts of the ileum was markedly reduced in the immune animals.
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