The prediction role of indexes of circulating adipokines for common anthropometric and nutritional characteristics of obesity in the obese Central European population
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
24854812
DOI
10.1016/j.eatbeh.2014.03.001
PII: S1471-0153(14)00027-0
Knihovny.cz E-zdroje
- Klíčová slova
- Adipokine, Correlation, Index, Leptin, Nutrition, Obesity,
- MeSH
- adipokiny krev MeSH
- adiponektin krev MeSH
- AgRP protein krev MeSH
- antropometrie * MeSH
- biologické markery krev MeSH
- cytokiny krev MeSH
- dieta statistika a číselné údaje MeSH
- dospělí MeSH
- GPI-vázané proteiny krev MeSH
- komplement - faktor D analýza MeSH
- lektiny krev MeSH
- leptin krev MeSH
- leptinové receptory krev MeSH
- lidé středního věku MeSH
- lidé MeSH
- nikotinamidfosforibosyltransferasa krev MeSH
- nutriční stav * MeSH
- obezita krev MeSH
- resistin krev MeSH
- ukazatele zdravotního stavu * MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- Názvy látek
- adipokiny MeSH
- adiponektin MeSH
- AgRP protein MeSH
- biologické markery MeSH
- cytokiny MeSH
- GPI-vázané proteiny MeSH
- ITLN1 protein, human MeSH Prohlížeč
- komplement - faktor D MeSH
- lektiny MeSH
- leptin MeSH
- leptinové receptory MeSH
- nikotinamidfosforibosyltransferasa MeSH
- resistin MeSH
AIMS: This study was designed to investigate the relationship between 8 selected adipokines (leptin, leptin receptor, adiponectin, agouti-related peptide, omentin, visfatin, adipsin and resistin), dietary composition and anthropometric parameters found in the Central European obese population. METHODS: A total of 65 unrelated obese Central European Caucasian individuals were recruited for the study. Phenotypic measurements included weight, height, BMI, lean body mass, fat mass, body fat, waist and hip circumference, waist-hip ratio (WHR) and skinfold thickness. Participants completed standardized self-reported 7-day food records. Plasma levels of leptin, leptin receptor, adiponectin, agouti-related peptide (AgRP), resistin, adipsin, omentin and visfatin were examined using ELISA. RESULTS: Multiple associations (weight, height, percentage of body fat, waist circumference, hip circumference, WHR and sum of skinfold thickness) with the circulation levels of the investigated adipokines were identified. Leptin-Leptin receptor (L-LR) levels were found to correlate with total energy intake and macronutrients while adipsin was found to strongly correlate with multiple adipokines. Furthermore, the L-LR index was found to constitute a more accurate description of the relationship between BMI and body weight than individual measurements and the Ag-LR index was found to strongly correlate with both anthropometric and dietary characteristics. CONCLUSION: Following confirmation on larger population samples and on samples of different ethnicities, the reported adipokine indexes could become a useful tool for estimating nutritional status and predicting the body composition of specific patient groups.
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