Schizophrenia and Toxoplasma gondii: an undervalued association?
Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu úvodníky, práce podpořená grantem
- Klíčová slova
- dopamine, manipulation hypothesis, mental disorder, parasite, schizophrenia, toxoplasmosis,
- MeSH
- lidé MeSH
- protilátky protozoální krev MeSH
- schizofrenie krev diagnóza epidemiologie MeSH
- Toxoplasma izolace a purifikace MeSH
- toxoplazmóza krev diagnóza epidemiologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- práce podpořená grantem MeSH
- úvodníky MeSH
- Názvy látek
- protilátky protozoální MeSH
The existence of an association between schizophrenia and an infection by the protozoan parasite Toxoplasma gondii has been suspected since the 1950s. Two significant phenomena first garnered the attention of the psychiatric community toward toxoplasmosis, the illness precipitated by an infection of the parasite. Transient symptoms of acute toxoplasmosis sometimes resemble the clinical picture of paranoid schizophrenia. Many studies have also found an increased seroprevalence of toxoplasmosis in clients of mental health institutions in comparison with members of control populations. We have had to wait until the first decade of our millennium for several independent research teams to make discoveries that would shed light on the possible mechanisms that link the Toxoplasma parasite to schizophrenia.
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