Electrochemical analysis of a novel ferrocene derivative as a potential antitumor drug
Language English Country Great Britain, England Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26203467
DOI
10.1039/c5an00958h
Knihovny.cz E-resources
- MeSH
- Electrochemical Techniques * MeSH
- Electrodes MeSH
- Humans MeSH
- Metallocenes MeSH
- MCF-7 Cells MeSH
- Cell Line, Tumor MeSH
- Antineoplastic Agents analysis pharmacology MeSH
- Reactive Oxygen Species chemistry MeSH
- Cell Survival drug effects MeSH
- Ferrous Compounds chemistry pharmacology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- ferrocene MeSH Browser
- Metallocenes MeSH
- Antineoplastic Agents MeSH
- Reactive Oxygen Species MeSH
- Ferrous Compounds MeSH
Ferrocenes represent an interesting group of drugs with potential antitumor properties. Moreover, their electronic properties make them suitable for electrochemical studies. We determined an uptake of a novel ferrocene derivative in low μM concentrations by selected cancer cell lines and showed its localization predominantly in cytoplasm, using glassy carbon electrodes.
References provided by Crossref.org
