Orthostatic hypotension is associated with decreased cerebrospinal fluid levels of chromogranin A in early stage of Parkinson disease
Language English Country Germany Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26359267
DOI
10.1007/s10286-015-0302-1
PII: 10.1007/s10286-015-0302-1
Knihovny.cz E-resources
- Keywords
- Cerebrospinal fluid, Chromogranin A, Orthostatic hypotension, Parkinson’s disease,
- MeSH
- Biomarkers cerebrospinal fluid MeSH
- Chromogranin A cerebrospinal fluid MeSH
- Middle Aged MeSH
- Humans MeSH
- Hypotension, Orthostatic diagnosis epidemiology MeSH
- Parkinson Disease cerebrospinal fluid diagnosis epidemiology MeSH
- Tilt-Table Test methods MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Biomarkers MeSH
- Chromogranin A MeSH
An association between the CSF chromogranin A (CgA) and orthostatic blood pressure changes was investigated in 20 patients in the early stage of Parkinson disease (PD). There was a positive correlation between the CSF CgA and diastolic blood pressure change, when CSF CgA levels were lower in patients with orthostatic hypotension (OH). Decreased CSF CgA may be useful in predicting OH in the early stage of PD.
Department of Laboratory Medicine Central Moravian Hospital County Inc Prostejov Czech Republic
Department of Medicine Central Moravian Hospital County Inc Prostejov Czech Republic
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