T-type channels: release a brake, engage a gear
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články
PubMed
26488564
PubMed Central
PMC4961007
DOI
10.1080/19336950.2015.1106655
Knihovny.cz E-zdroje
- Klíčová slova
- CaV3.1, CaV3.3, T-type calcium channels, channel gating, gating brake, low-voltage activated calcium channels, pore opening, voltage-dependence of activation,
- MeSH
- buněčná membrána metabolismus MeSH
- gating iontového kanálu MeSH
- iontový transport MeSH
- lidé MeSH
- membránové potenciály fyziologie MeSH
- neurony cytologie metabolismus MeSH
- proteinové domény MeSH
- regulace genové exprese MeSH
- sekundární struktura proteinů MeSH
- termodynamika MeSH
- vápník metabolismus MeSH
- vápníkové kanály - typ T genetika metabolismus MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- CACNA1G protein, human MeSH Prohlížeč
- CACNA1H protein, human MeSH Prohlížeč
- CACNA1I protein, human MeSH Prohlížeč
- vápník MeSH
- vápníkové kanály - typ T MeSH
doi: 10.1007/s00424-015-1728-y PubMed
Zobrazit více v PubMed
Perez-Reyes E. Molecular physiology of low-voltage-activated t-type calcium channels. Physiol Rev 2003; 83:117–61; PMID:12506128; http://dx.doi.org/10.1152/physrev.00018.2002 PubMed DOI
Perez-Reyes E. Characterization of the gating brake in the I-II loop of CaV3 T-type calcium channels. Channels (Austin) 2010; 4:453–8. PubMed PMC
Baumgart JP, Vitko I, Bidaud I, Kondratskyi A, Lory P, Perez-Reyes E. I-II loop structural determinants in the gating and surface expression of low voltage-activated calcium channels. PLoS One 2008; 3:e2976; PMID:18714336; http://dx.doi.org/10.1371/journal.pone.0002976 PubMed DOI PMC
Karmažínová M, Jašková K, Griac P, Perez-Reyes E, Lacinová Ľ. Contrasting the roles of the I-II loop gating brake in CaV3.1 and CaV3.3 calcium channels. Pflugers Arch 2015; 467:2519-27; http://dx.doi.org/10.1007/s00424-015-1728-y PubMed DOI
Lacinová L, Klugbauer N, Hofmann F. Gating of the expressed Cav3.1 calcium channel. FEBS Lett 2002; 531:235–40; http://dx.doi.org/10.1016/S0014-5793(02)03509-3 PubMed DOI
Karmažínová M, Baumgart JP, Perez-Reyes E, Lacinová L. The voltage dependence of gating currents of the neuronal CaV3.3 channel is determined by the gating brake in the I-II loop. Pflugers Arch 2011; 461:461–8; http://dx.doi.org/10.1007/s00424-011-0937-2 PubMed DOI PMC
García-Caballero A, Gadotti VM, Stemkowski P, Weiss N, Souza IA, Hodgkinson V, Bladen C, Chen L, Hamid J, Pizzoccaro A, et al. . The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity. Neuron 2014; 83:1144–58; http://dx.doi.org/10.1016/j.neuron.2014.07.036 PubMed DOI
Weiss N, Hameed S, Fernández-Fernández JM, Fablet K, Karmazinova M, Poillot C, Proft J, Chen L, Bidaud I, Monteil A, et al. . A Ca(v)3.2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis. J Biol Chem 2012; 287:2810–8; PMID:22130660; http://dx.doi.org/10.1074/jbc.M111.290882 PubMed DOI PMC
A Cav3.2/Stac1 molecular complex controls T-type channel expression at the plasma membrane
