Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go? - Pospisilova, Sarka; Sutton, Lesley-Ann; Malcikova, Jitka; Tausch, Eugen; Rossi, Davide; Montserrat, Emili; Moreno, Carol; Stamatopoulos, Kostas; Gaidano, Gianluca; Rosenquist, Richard; Ghia, Paolo; European Research Initiative on CLL (ERIC) (Haematologica, 2016)
Keywords: Purines; Sulfonamides; exprese genu; cílená molekulární terapie; Gene Expression; Piperidines; Gene Frequency; chinazolinony; Agammaglobulinaemia Tyrosine Kinase; protinádorové látky; Quinazolinones; Class I Phosphatidylinositol 3-Kinases; tyrosinkinasy; Adenine; High-Throughput Nucleotide Sequencing; prognóza; adenin; Pyrazoles; Pyrimidines; puriny; nádorový supresorový protein p53; piperidiny; fosfatidylinositol-3-kinasy třídy I; proteinkinasa BTK; frekvence genu; Leukemia, Lymphocytic, Chronic, B-Cell; lidé; Biomarkers, Tumor; Humans; pyrimidiny; vysoce účinné nukleotidové sekvenování; bicyklické sloučeniny heterocyklické; Bridged Bicyclo Compounds, Heterocyclic; Molecular Targeted Therapy; Prognosis; Alleles; pyrazoly; sulfonamidy; alely; chronická lymfatická leukemie; Protein-Tyrosine Kinases; nádorové biomarkery; Tumor Suppressor Protein p53; Antineoplastic Agents