Ability to downregulate the level of cyclin-dependent kinase inhibitor p27Kip1 after DNA damage is retained in chronic lymphocytic leukemia cells with functional ATM/p53 signaling pathway - Raskova Kafkova, Leona; Navrkalova, Veronika; Jarosova, Marie; Loja, Tomas; Chovancova, Jana; Kucerova, Jana; Kriegova, Eva; Prochazka, Vit; Novak, Zdenek; Simkova, Dana; Pospisilova, Sarka; Divoky, Vladimir (Leukemia & lymphoma, 2017)
Keywords: nádorový supresorový protein p53; senioři; Cell Cycle; signální transdukce; DNA Damage; průtoková cytometrie; Cyclin-Dependent Kinase Inhibitor p27; poškození DNA; down regulace; ATM protein; Signal Transduction; mutace; Tumor Suppressor Protein p53; Adult; Down-Regulation; buněčný cyklus; western blotting; Flow Cytometry; Blotting, Western; chronická lymfatická leukemie; Mutation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Ataxia Telangiectasia Mutated Proteins; dospělí; Aged; inhibitor p27 cyklin-dependentní kinasy; lidé