Copy-number variation of housekeeping gene rpl13a in rat strains selected for nervous system excitability
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
28192165
DOI
10.1016/j.mcp.2017.02.004
PII: S0890-8508(17)30016-6
Knihovny.cz E-resources
- Keywords
- Bone marrow, Copy number variation (CNV), Hippocampus, Nervous system excitability, Quantitative real-time multicolor multiplex PCR (qmPCR), Rat,
- MeSH
- Hippocampus metabolism physiology MeSH
- Cortical Excitability genetics physiology MeSH
- Bone Marrow metabolism physiology MeSH
- Rats MeSH
- Nervous System Physiological Phenomena genetics MeSH
- Ribosomal Proteins genetics MeSH
- DNA Copy Number Variations genetics MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Ribosomal Proteins MeSH
- Rpl13a protein, rat MeSH Browser
We evaluated copy number variation (CNV) for four genes in rat strains differing in nervous system excitability. rpl13a copy number is significantly reduced in hippocampus and bone marrow in rats with a high excitability threshold and stress. The observed phenomenon may be associated with a role for rpl13a in lipid metabolism.
References provided by Crossref.org
