Medical devices have an essential part in healthcare system in recent years, such as usage of heart valves, several types of stents and implants devices in patients. However, bacterial infection of medical devices causes critical issues for patients due to attachment of bacteria and formation of biofilm onto the medical devices. Therefore, finding an effective antibacterial coating to prevent biofilm formation and infection is our goal. In this study, we developed silver/chitosan nanocomposites for antimicrobial coating system by chemical and green methods using sodium borohydride and linden extract, respectively. Silver is known as a strong inorganic antimicrobial agent to kill bacteria by inactivating enzymes and dysfunction bacterial cell membranes. By immobilizing silver nanoparticles on chitosan biopolymer can prevent agglomeration of nanoparticles, besides it can improve the biocompatibility. We characterized properties of our silver chitosan nanocomposites samples using particle size distribution, ultraviolet-visible spectroscopy, X-ray diffraction analysis and scanning electron microscopy. Effective antimicrobial film preventing biofilm formation on medical devices was designed. Antimicrobial testing confirmed antimicrobial properties however variable for each type of nanosilver.

Engineering Faculty Department of Metallurgical and Materials Engineering Sakarya University Esentepe Campus 54187 Sakarya Turkey

Nanoscience and Nanoengineering Faculty Sakarya University Esentepe Campus 54187 Sakarya Turkey

Nanotechnology Centre VŠB Technical University of Ostrava 17 listopadu 15 708 33 Ostrava Poruba Czech Republic

National Reference Laboratory Institute of Public Health in Ostrava Partyzánské náměstí 7 702 00 Ostrava Czech Republic

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