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Exploring the molecular basis of sexual dimorphism in bladder cancer

. 2020 Sep ; 17 (9) : 487-488.

Language English Country England, Great Britain Media print

Document type Journal Article, Comment

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PubMed 32444779
DOI 10.1038/s41585-020-0339-3
PII: 10.1038/s41585-020-0339-3
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Dobruch, J. et al. Gender and bladder cancer: a collaborative review of etiology, biology, and outcomes. Eur. Urol. 69, 300–310 (2016). DOI

Yuan, Y. et al. Comprehensive characterization of molecular differences in cancer between male and female patients. Cancer Cell 29, 711–722 (2016). DOI

Kamoun, A. et al. A consensus molecular classification of muscle-invasive bladder cancer. Eur. Urol. 77, 420–433 (2019). DOI

de Jong, J. J. et al. Distribution of molecular subtypes in muscle-invasive bladder cancer is driven by sex-specific differences. Eur. Urol. Oncol. https://doi.org/10.1016/j.euo.2020.02.010 (2020). PubMed DOI

Trilla-Fuertes, L. et al. Biological molecular layer classification of muscle-invasive bladder cancer opens new treatment opportunities. BMC Cancer 19, 636 (2019). DOI

Jahrreiss, V., Pradere, B., Laukhtina, E., Mori, K. & Shariat, S. F. Catalog of exogenous risk factors for bladder carcinogenesis. Curr. Opin. Urol. 30, 449–456 (2020). DOI

Krimphove, M. J. et al. Sex-specific differences in the quality of treatment of muscle-invasive bladder cancer do not explain the overall survival discrepancy. Eur. Urol. Focus https://doi.org/10.1016/j.euf.2019.06.001 (2019). PubMed DOI

Lucca, I., Klatte, T., Fajkovic, H., de Martino, M. & Shariat, S. F. Gender differences in incidence and outcomes of urothelial and kidney cancer. Nat. Rev. Urol. 12, 653 (2015). DOI

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