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A new silver dressing, StopBac, used in the prevention of surgical site infections

. 2022 Jan ; 19 (1) : 29-35. [epub] 20210327

Language English Country Great Britain, England Media print-electronic

Document type Journal Article

Grant support
16-28375A Ministry of Health of the Czech Republic

Ideal dressings of surgical wounds should provide moist, semi-permeable, and antiseptic environments for optimal wound healing. To maximise patient comfort, surgical dressings must be hypoallergenic, not restrict movement, and allow patients to manage their personal hygiene. From the aspect of health care personnel, dressings should enable visual monitoring of the wound without the need for removing them, thus reducing the number of dressing changes. The active antimicrobial effect of silver cations has been demonstrated by many studies. StopBac is a unique surgical dressing based on the sol-gel process. Silver cations are bound in a colloidal solution in an organic-inorganic hybrid organosilicate oligomer. This gel is deposited on a pad using spray atomisation. The result is a polymer nanolayer matrix with prolonged and controlled release of silver ions. This pad forms part of a waterproof hypoallergenic transparent adhesive bandage. The goal of this study was to prospectively evaluate the ability of StopBac to prevent surgical site infections (SSIs) in patients after abdominal surgery. The secondary goal was to compare costs and determine the properties of this new material. A total of 32 patients were included in the study. The patients were followed up until their surgical wounds healed completely. An SSI occurred only in one patient.

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Woodmansey EJ, Roberts CD. Appropriate use of dressings containing nanocrystalline silver to support antimicrobial stewardship in wounds. Int Wound J. 2018;15(6):1025‐1032. 10.1111/iwj.12969. PubMed DOI PMC

Cooper R, Kirketerp‐Moller K. Non‐antibiotic antimicrobial interventions and antimicrobial stewardship in wound care. J Wound Care. 2018;27(6):355‐377. 10.12968/jowc.2018.27.6.355. PubMed DOI

Dissemond J, Bottrich JG, Braunwarth H, Hilt J, Wilken P, Munter KC. Evidence for silver in wound care—meta‐analysis of clinical studies from 2000‐2015. J Dtsch Dermatol Ges. 2017;15(5):524‐535. 10.1111/ddg.13233. PubMed DOI

Li HZ, Zhang L, Chen JX, Zheng Y, Zhu XN. Silver‐containing dressing for surgical site infection in clean and clean‐contaminated operations: a systematic review and meta‐analysis of randomized controlled trials. J Surg Res. 2017;215:98‐107. 10.1016/j.jss.2017.03.040. PubMed DOI

Walker M, Parsons D. The biological fate of silver ions following the use of silver‐containing wound care products—a review. Int Wound J. 2014;11(5):496‐504. 10.1111/j.1742-481X.2012.01115.x. PubMed DOI PMC

McDonnell G, Russell AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev. 1999;12(1):147‐179. PubMed PMC

Slamborova I, Zajicova V, Karpiskova J, Exnar P, Stibor I. New type of protective hybrid and nanocomposite hybrid coatings containing silver and copper with an excellent antibacterial effect especially against MRSA. Korean J Couns Psychother. 2013;33(1):265‐273. 10.1016/j.msec.2012.08.039. PubMed DOI

Abbaszadegan A, Gholami A, Abbaszadegan S, et al. The effects of different ionic liquid coatings and the length of alkyl chain on antimicrobial and cytotoxic properties of silver nanoparticles. Iran Endod J. 2017;12(4):481‐487. 10.22037/iej.v12i4.17905. PubMed DOI PMC

Yamanaka M, Hara K, Kudo J. Bactericidal actions of a silver ion solution on Escherichia coli, studied by energy‐filtering transmission electron microscopy and proteomic analysis. Appl Environ Microbiol. 2005;71(11):7589‐7593. 10.1128/AEM.71.11.7589-7593.2005. PubMed DOI PMC

Lopez‐Carballo G, Higueras L, Gavara R, Hernandez‐Munoz P. Silver ions release from antibacterial chitosan films containing in situ generated silver nanoparticles. J Agric Food Chem. 2013;61(1):260‐267. 10.1021/jf304006y. PubMed DOI

Fang Y, Gurusamy KS, Wang Q, et al. Meta‐analysis of randomized clinical trials on safety and efficacy of biliary drainage before surgery for obstructive jaundice. Br J Surg. 2013;100(12):1589‐1596. 10.1002/bjs.9260. PubMed DOI

Wu JM, Ho TW, Yen HH, et al. Endoscopic retrograde biliary drainage causes intra‐abdominal abscess in pancreaticoduodenectomy patients: an important but neglected risk factor. Ann Surg Oncol. 2019;26(4):1086‐1092. 10.1245/s10434-019-07189-y. PubMed DOI

Hennessey DB, Burke JP, Ni‐Dhonochu T, Shields C, Winter DC, Mealy K. Preoperative hypoalbuminemia is an independent risk factor for the development of surgical site infection following gastrointestinal surgery: a multi‐institutional study. Ann Surg. 2010;252(2):325‐329. 10.1097/SLA.0b013e3181e9819a. PubMed DOI

Ceppa EP, Pitt HA, House MG, et al. Reducing surgical site infections in hepatopancreatobiliary surgery. HPB (Oxford). 2013;15(5):384‐391. 10.1111/j.1477-2574.2012.00604.x. PubMed DOI PMC

Takahashi Y, Takesue Y, Fujiwara M, et al. Risk factors for surgical site infection after major hepatobiliary and pancreatic surgery. J Infect Chemother. 2018;24(9):739‐743. 10.1016/j.jiac.2018.05.007. PubMed DOI

Leaper D. Appropriate use of silver dressings in wounds: international consensus document. Int Wound J. 2012;9(5):461‐464. 10.1111/j.1742-481X.2012.01091.x. PubMed DOI PMC

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