This work presents a case series of four children diagnosed with severe cerebrovascular disease in association with recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, yet no patient from the group met typical diagnostic criteria for multisystem inflammatory syndrome in children. Our aim was to highlight the possible vascular involvement and coagulopathies associated with SARS-CoV-2 infection in the pediatric population. Further data are needed to better understand the pathophysiological basis of this condition in children and to ensure its optimal management.

Department of Pediatric Anesthesiology and Intensive Care Medicine Faculty of Medicine of Masaryk University University Hospital Brno Brno Czech Republic; Department of Simulation Medicine Faculty of Medicine Masaryk University Brno Brno Czech Republic

Department of Pediatric Hematology Faculty of Medicine of Masaryk University University Hospital Brno Brno Czech Republic

Department of Pediatric Infectious Diseases Faculty of Medicine of Masaryk University University Hospital Brno Brno Czech Republic

Department of Pediatric Neurology Faculty of Medicine of Masaryk University University Hospital Brno Brno Czech Republic

Department of Pediatric Radiology Faculty of Medicine of Masaryk University University Hospital Brno Brno Czech Republic

Pediatr Neurol. 2022 Nov;136:34. doi: 10.1016/j.pediatrneurol.2022.07.015. PubMed

Pediatr Neurol. 2023 May;142:31. doi: 10.1016/j.pediatrneurol.2023.02.002. PubMed

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