Silver-Based Dressings in the Prevention of the Incisional Surgical Site Infection: A Prospective Multicenter Observational Controlled Trial
Language English Country United States Media print-electronic
Document type Journal Article, Multicenter Study, Observational Study, Randomized Controlled Trial
PubMed
35930248
DOI
10.1089/sur.2022.084
Knihovny.cz E-resources
- Keywords
- primary wound healing, silver ions, silver-based dressing, sol-gel, surgical site infection,
- MeSH
- Surgical Wound Infection * epidemiology etiology prevention & control MeSH
- Humans MeSH
- Bandages * adverse effects MeSH
- Prospective Studies MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Observational Study MeSH
- Randomized Controlled Trial MeSH
Background: A new silver-based dressing has been designed to reduce surgical sited infections. Patients and Methods: A prospective multicenter observational study was conducted from January 2020 to October 2021. Patients with and without silver-based dressing after surgical incision were observed and their data analyzed. The study aimed to assess the incidence of incisional surgical site infection and primary healing after general surgery procedures. Results: Overall, 218 patients with silver-based (n = 109) and conventional silver-free dressing (n = 109) were analyzed. Surgical site infection (SSI) and primary incision healing were reported in 10 (9.2%) versus 21 (19.3%) (p = 0.037) and in 95 (87.2%) versus 86 (78.9%) (p = 0.107) patients treated with and without silver-based dressing, respectively. Conclusions: Silver-based dressing demonstrated a lower incidence of incisional SSI and improved primary healing in comparison with patients in whom conventional non-silver-based dressing has been used.
Department of Surgery The University Hospital Brno Czech Republic
Faculty of Biomedical Engineering Czech Technical University Prague Kladno Czech Republic
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