Incidence of surgical site infections after cervical spine surgery: results of a single-center cohort study adhering to multimodal preventive wound control protocol

. 2023 Jul ; 33 (5) : 1997-2004. [epub] 20220914

Jazyk angličtina Země Francie Médium print-electronic

Typ dokumentu časopisecké články, pozorovací studie

Perzistentní odkaz   https://www.medvik.cz/link/pmid36102993
Odkazy

PubMed 36102993
PubMed Central PMC10276122
DOI 10.1007/s00590-022-03379-9
PII: 10.1007/s00590-022-03379-9
Knihovny.cz E-zdroje

PURPOSE: The incidence of surgical site infections is considered a relevant indicator of perioperative and postoperative care quality. The aim of this study is to analyze and evaluate SSIs after elective cervical spine surgery under the guidance of our preventive multimodal wound protocol. METHODS: A monocentric observational cohort study analyzed 797 patients who underwent cervical spine surgery from 2005 to 2010 (mean age 51.58 ± 11.74 year, male 56.09%, mean BMI 26.87 ± 4.41, ASA score 1-2 in 81.68% of patients), fulfilling the entry criteria: (1) cervical spine surgery performed by neurosurgeons (degenerative disease 85.19%, trauma 11.04%, tumor 3.76%), (2) elective surgery, (3) postoperative care in our neurointensive care unit. Our preventive wound control protocol management focused mainly on antibiotic prophylaxis, wound hygiene regime, and drainage equipment. All wound complications and surgical site infections were monitored up for 1 year after surgery. RESULTS: We had only 2 (0.25%) patients with SSI after cervical spine surgery-one organ/space infection (osteomyelitis, primary due to liquorrhea) after anterior surgical approach, and one deep surgical site infection (due to dehiscence) after posterior approach. We had 17 (2.13%) patients with some wound complications (secretion 7, dehiscence 4, hematoma 1, edema 3, and liquorrhea 2) that were not classified as SSI according to the CDC guidelines. CONCLUSION: Concerning our study population of patients undergoing elective cervical surgery, with ASA scores 1-2 in 81.68% of our patients, the incidence of SSI was 0.14% after anterior surgical approach, 1.4% after posterior surgical approach, and 0.25% altogether in the referred cohort.

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January 2021. CDC 9 - 1 Surgical Site Infection Event (SSI) https://www.cdc.gov/nhsn/pdfs/pscmanual/9pscssicurrent.pdf. Accessed from 15th Sep 2021

van Niekerk JM, Vos MC, Stein A, Braakman-Jansen LMA, Voor Int Holt AF, van Gemert-Pijnen JEWC. Risk factors for surgical site infections using a data-driven approach. PLoS ONE. 2020;15(10):e0240995. doi: 10.1371/journal.pone.0240995. PubMed DOI PMC

Weimann A, Braga M, Carli F, Higashiguchi T, Hübner M, Klek S, Laviano A, Ljungqvist O, Lobo DN, Martindale R, Waitzberg DL, Bischoff SC, Singer P. ESPEN guideline: clinical nutrition in surgery. Clin Nutr. 2017;36(3):623–650. doi: 10.1016/j.clnu.2017.02.013. PubMed DOI

Yao R, Zhou H, Choma TJ, Kwon BK, Street J. Surgical site infection in spine surgery: who is at risk? Glob Spine J. 2018;8(4 Suppl):5S–30S. doi: 10.1177/2192568218799056. PubMed DOI PMC

Kolasiński W. Surgical site infections - review of current knowledge, methods of prevention. Pol Przegl Chir. 2018;91(4):41–47. doi: 10.5604/01.3001.0012.7253. PubMed DOI

Greene LR. Guide to the elimination of orthopedic surgery surgical site infections: an executive summary of the Association for Professionals in Infection Control and Epidemiology elimination guide. Am J Infect Control. 2012;40(4):384–386. doi: 10.1016/j.ajic.2011.05.011. PubMed DOI

Bratzler DW, Dellinger EP, Olsen KM, Perl TM, Auwaerter PG, Bolon MK, Fish DN, Napolitano LM, Sawyer RG, Slain D, Steinberg JP, Weinstein RA, American Society of Health-System Pharmacists (ASHP) Infectious Diseases Society of America (IDSA) Surgical Infection Society (SIS) Society for Healthcare Epidemiology of America (SHEA) Clinical practice guidelines for antimicrobial prophylaxis in surgery. Surg Infect (Larchmt) 2013;14(1):73–156. doi: 10.1089/sur.2013.9999. PubMed DOI

de Lissovoy G, Fraeman K, Hutchins V, Murphy D, Song D, Vaughn BB. Surgical site infection: incidence and impact on hospital utilization and treatment costs. Am J Infect Control. 2009;37(5):387–397. doi: 10.1016/j.ajic.2008.12.010. PubMed DOI

Point prevalence survey of healthcare-associated infections and antimicrobial use in European acute care hospitals (2013) European Centre for Disease Prevention and Control - ECDPC: Stockholm

Gottrup F. Prevention of surgical-wound infections. N Engl J Med. 2000;342(3):202–204. doi: 10.1056/NEJM200001203420310. PubMed DOI

Zhou J, Wang R, Huo X, Xiong W, Kang L, Xue Y. Incidence of surgical site infection after spine surgery: a systematic review and meta-analysis. Spine (Phila Pa 1976) 2020;45(3):208–216. doi: 10.1097/BRS.0000000000003218. PubMed DOI

Tamai K, Wang C, Heindel P, Paholpak P, Buser Z, Wang JC. Perioperative catheter use as a risk factor for surgical site infection after cervical surgery: an analysis of 39,893 patients. Spine (Phila Pa 1976) 2019;44(3):E157–E161. doi: 10.1097/BRS.0000000000002790. PubMed DOI

Yee TJ, Swong K, Park P. Complications of anterior cervical spine surgery: a systematic review of the literature. J Spine Surg. 2020;6(1):302–322. doi: 10.21037/jss.2020.01.14. PubMed DOI PMC

Fountas KN, Kapsalaki EZ, Nikolakakos LG, Smisson HF, Johnston KW, Grigorian AA, Lee GP, Robinson JS., Jr Anterior cervical discectomy and fusion associated complications. Spine (Phila Pa 1976) 2007;32(21):2310–2317. doi: 10.1097/BRS.0b013e318154c57e. PubMed DOI

Ariyo P, Zayed B, Riese V, Anton B, Latif A, Kilpatrick C, Allegranzi B, Berenholtz S. Implementation strategies to reduce surgical site infections: a systematic review. Infect Control Hosp Epidemiol. 2019;40(3):287–300. doi: 10.1017/ice.2018.355. PubMed DOI

Aleem IS, Tan LA, Nassr A, Riew KD. Surgical site infection prevention following spine surgery. Global Spine J. 2020;10(1 Suppl):92S–98S. doi: 10.1177/2192568219844228. PubMed DOI PMC

Global Guidelines for the Prevention of Surgical Site Infection (2018) Geneva: World Health Organization. (PMID: 30689333) PubMed

Suchomel M, Kundi M, Pittet D, Rotter ML. Modified World Health Organization hand rub formulations comply with European efficacy requirements for preoperative surgical hand preparations. Infect Control Hosp Epidemiol. 2013;34(3):245–250. doi: 10.1086/669528. PubMed DOI

Monegro AF, Muppidi V, Regunath H (2021) Hospital acquired infections. In StatPearls. (PMID: 28722887) PubMed

Serra-Burriel M, Keys M, Campillo-Artero C, Agodi A, Barchitta M, Gikas A, Palos C, López-Casasnovas G. Impact of multi-drug resistant bacteria on economic and clinical outcomes of healthcare-associated infections in adults: Systematic review and meta-analysis. PLoS ONE. 2020;15(1):e0227139. doi: 10.1371/journal.pone.0227139. PubMed DOI PMC

Spatenkova V, Bradac O, Jindrisek Z, Hradil J, Fackova D, Halacova M. Risk factors associated with surgical site infections after thoracic or lumbar surgery: a 6-year single centre prospective cohort study. J Orthop Surg Res. 2021;16(1):265. doi: 10.1186/s13018-021-02418-1. PubMed DOI PMC

Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Am J Infect Control. 1992;20(5):271–274. doi: 10.1016/s0196-6553(05)80201-9. PubMed DOI

Garner BH, Anderson DJ. Surgical Site Infections: An Update. Infect Dis Clin North Am. 2016;30(4):909–929. doi: 10.1016/j.idc.2016.07.010. PubMed DOI

Beiner JM, Grauer J, Kwon BK, Vaccaro AR. Postoperative wound infections of the spine. Neurosurg Focus. 2003;15(3):E14. doi: 10.3171/foc.2003.15.3.14. PubMed DOI

Weinstein MA, McCabe JP, Cammisa FP., Jr Postoperative spinal wound infection: a review of 2,391 consecutive index procedures. J Spinal Disord. 2000;13(5):422–426. doi: 10.1097/00002517-200010000-00009. PubMed DOI

Fang A, Hu SS, Endres N, Bradford DS. Risk factors for infection after spinal surgery. Spine (Phila Pa 1976) 2005;30(12):1460–1465. doi: 10.1097/01.brs.0000166532.58227.4f. PubMed DOI

Schimmel JJ, Horsting PP, de Kleuver M, Wonders G, van Limbeek J. Risk factors for deep surgical site infections after spinal fusion. Eur Spine J. 2010;19(10):1711–1719. doi: 10.1007/s00586-010-1421-y. PubMed DOI PMC

Spagnolo AM, Ottria G, Amicizia D, Perdelli F, Cristina ML. Operating theatre quality and prevention of surgical site infections. J Prev Med Hyg. 2013;54(3):131–137. PubMed PMC

Cizik AM, Lee MJ, Martin BI, Bransford RJ, Bellabarba C, Chapman JR, Mirza SK. Using the spine surgical invasiveness index to identify risk of surgical site infection: a multivariate analysis. J Bone Joint Surg Am. 2012;94(4):335–342. doi: 10.2106/JBJS.J.01084. PubMed DOI PMC

Pull ter Gunne AF, Cohen DB. Incidence, prevalence, and analysis of risk factors for surgical site infection following adult spinal surgery. Spine (Phila Pa 1976) 2009;34(13):1422–1428. doi: 10.1097/BRS.0b013e3181a03013. PubMed DOI

Levi AD, Dickman CA, Sonntag VK. Management of postoperative infections after spinal instrumentation. J Neurosurg. 1997;86(6):975–980. doi: 10.3171/jns.1997.86.6.0975. PubMed DOI

Woods BI, Rosario BL, Chen A, Waters JH, Donaldson W, 3rd, Kang J, Lee J. The association between perioperative allogeneic transfusion volume and postoperative infection in patients following lumbar spine surgery. J Bone Joint Surg Am. 2013;95(23):2105–2110. doi: 10.2106/JBJS.L.00979. PubMed DOI PMC

Ehlenbach WJ, Curtis JR. Noninvasive ventilation for patients near the end of life: what do we know and what do we need to know? Crit Care Med. 2008;36(3):1003–1004. doi: 10.1097/CCM.0B013E318165FD78. PubMed DOI PMC

Spatenkova V, Bradac O, Fackova D, Bohunova Z, Suchomel P. Low incidence of multidrug-resistant bacteria and nosocomial infection due to a preventive multimodal nosocomial infection control: a 10-year single centre prospective cohort study in neurocritical care. BMC Neurol. 2018;18(1):23. doi: 10.1186/s12883-018-1031-6. PubMed DOI PMC

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