Ventricular fibrillation and arrhythmia associated with cardiac fibromas involving both ventricles in a 1.5-year-old girl

. 2023 ; 33 (3) : 218-222. [epub] 20230207

Status PubMed-not-MEDLINE Jazyk angličtina Země Německo Médium print-electronic

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/pmid36778761

This article reports the autopsy findings of a 1.5-year-old girl with no history of previous hospital admission who suddenly collapsed at home. After 45 minutes of resuscitation efforts, the cardiac activity was restored. During hospitalization, she had ventricular arrhythmia and extremely elevated cardiac troponin levels. Internal examination and immunohistochemistry revealed cardiac fibromas of the right and left ventricles and extensive hypoxic myocardial damage. The right ventricular fibroma demonstrated interdigitating and entrapped myocardium visible at the edges and within the central portion of the tumor. The left ventricular fibroma originated in the subepicardial region and propagated towards the endocardium.

In diesem Artikel wird über die Autopsiebefunde eines 1,5-jährigen Mädchens ohne vorherige Krankenhauseinweisung berichtet, das plötzlich zu Hause zusammenbrach. Nach 45-minütigen Reanimationsbemühungen war die Herzaktivität wiederhergestellt. Während des Krankenhausaufenthalts litt sie unter ventrikulären Arrhythmien und extrem erhöhten kardialen Troponinspiegeln. Klinische Diagnostik und Immunhistochemie ergaben ein Herzfibrom des rechten und linken Ventrikels und einen ausgedehnten hypoxischen Myokardschaden. Das Fibrom des rechten Ventrikels zeigte ineinandergreifendes und eingeschlossenes Myokard, das an den Rändern und innerhalb des zentralen Teils des Tumors sichtbar war. Das linksventrikuläre Fibrom entstand in der subepikardialen Region und breitete sich zum Endokard aus.

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