Subspecific rodent taxa as the relevant host taxonomic level for mammarenavirus host specificity
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
36958216
DOI
10.1016/j.virol.2023.02.014
PII: S0042-6822(23)00037-5
Knihovny.cz E-resources
- Keywords
- Berega virus, Comparative phylogeography, Grammomys surdaster, Host genetic structure, Host jump, Host specificity, Mus minutoides, Ngerengere virus, Songea virus, Spill-over,
- MeSH
- Arenaviridae * genetics MeSH
- Phylogeography MeSH
- Host Specificity MeSH
- Murinae MeSH
- Rodent Diseases * MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Tanzania MeSH
Mastomys natalensis-borne mammarenaviruses appear specific to subspecific M. natalensis taxa rather than to the whole species. Yet mammarenaviruses carried by M. natalensis are known to spill over and jump hosts in northern sub-Saharan Africa. Phylogeographic studies increasingly show that, like M. natalensis, small mammals in sub-Saharan Africa are often genetically structured into several subspecific taxa. Other mammarenaviruses may thus also form virus-subspecific host taxon associations. To investigate this, and if mammarenaviruses carried by M. natalensis in southern Africa are less prone to spill-over, we screened 1225 non-M. natalensis samples from Tanzania where many small mammal taxa meet. We found mammarenavirus RNA in 6 samples. Genetic/genomic characterisation confirmed they were not spill-over from M. natalensis. We detected host jumps among rodent tribe members and an association between mammarenaviruses and subspecific taxa of Mus minutoides and Grammomys surdaster, indicating host genetic structure may be crucial to understand virus distribution and host specificity.
Institute of Vertebrate Biology of the Czech Academy of Sciences Květná 8 603 65 Brno Czech Republic
References provided by Crossref.org
