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Targeted-release budesonide modifies key pathogenic biomarkers in immunoglobulin A nephropathy: insights from the NEFIGAN trial

Wimbury, David
Author Wimbury, David Mayer IgA Nephropathy Laboratories, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
Muto, Masahiro
Author Muto, Masahiro Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan
Bhachu, Jasraj S
Author Bhachu, Jasraj S Mayer IgA Nephropathy Laboratories, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
Scionti, Katrin
Author Scionti, Katrin Mayer IgA Nephropathy Laboratories, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
Brown, Jeremy
Author Brown, Jeremy Mayer IgA Nephropathy Laboratories, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
Molyneux, Karen
Author Molyneux, Karen Mayer IgA Nephropathy Laboratories, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
Seikrit, Claudia
Author Seikrit, Claudia Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany
Maixnerová, Dita
Author Maixnerová, Dita Department of Nephrology, 1st Faculty of Medicine, General University Hospital, Charles University, Prague, Czech Republic
Pérez-Alós, Laura
Author Pérez-Alós, Laura Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Copenhagen, Denmark
Garred, Peter
Author Garred, Peter Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Copenhagen, Denmark
Floege, Jürgen
Author Floege, Jürgen Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany
Tesař, Vladimír
Author Tesař, Vladimír Department of Nephrology, 1st Faculty of Medicine, General University Hospital, Charles University, Prague, Czech Republic
Fellstrom, Bengt
Author Fellstrom, Bengt Department of Medical Sciences, Uppsala University, Uppsala University Hospital, Uppsala, Sweden
Coppo, Rosanna
Author Coppo, Rosanna Fondazione Ricerca Molinette, Regina Margherita Hospital, Turin, Italy
Barratt, Jonathan
Author Barratt, Jonathan Mayer IgA Nephropathy Laboratories, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK. Electronic address: jb81@leicester.ac.uk

Kidney international. 2024 Feb ; 105 (2) : 381-388. [epub] 20231125

Kidney Int
ISSN 1523-1755 | 0085-2538
Source

Language English Country United States Media print-electronic

Document type Journal Article

Persistent link https://www.medvik.cz/link/pmid38008160

PubMed 38008160
DOI 10.1016/j.kint.2023.11.003
PII: S0085-2538(23)00778-0
Knihovny.cz E-resources

Keywords
IgA nephropathy, chronic kidney disease, complement, cytokines, glomerulus, proteinuria,
MeSH
Biomarkers MeSH
Budesonide adverse effects MeSH
Kidney Glomerulus pathology MeSH
Glomerulonephritis, IGA * diagnosis drug therapy pathology MeSH
Immunoglobulin A MeSH
Humans MeSH
Proteinuria pathology MeSH
Check Tag
Humans MeSH
Publication type
Journal Article MeSH
Names of Substances
Biomarkers MeSH
Budesonide MeSH
Immunoglobulin A MeSH

Department of Medical Sciences Uppsala University Uppsala University Hospital Uppsala Sweden

Department of Nephrology 1st Faculty of Medicine General University Hospital Charles University Prague Czech Republic

Department of Nephrology Juntendo University Faculty of Medicine Tokyo Japan

Division of Nephrology and Clinical Immunology Rheinisch Westfälische Technische Hochschule Aachen University Aachen Germany

Fondazione Ricerca Molinette Regina Margherita Hospital Turin Italy

Laboratory of Molecular Medicine Department of Clinical Immunology Section 7631 Rigshospitalet Copenhagen Denmark

Mayer IgA Nephropathy Laboratories Department of Cardiovascular Sciences University of Leicester Leicester UK

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Targeted-release budesonide modifies key pathogenic biomarkers in immunoglobulin A nephropathy: insights from the NEFIGAN trial

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