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Pembrolizumab plus enfortumab vedotin in urothelial cancer

. 2024 Jul ; 21 (7) : 387-388.

Language English Country England, Great Britain Media print

Document type Journal Article

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PubMed 38267716
DOI 10.1038/s41585-024-00858-y
PII: 10.1038/s41585-024-00858-y
Knihovny.cz E-resources

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Powles, T. B. et al. LBA6 EV-302/KEYNOTE-A39: Open-label, randomized phase III study of enfortumab vedotin in combination with pembrolizumab (EV+P) vs chemotherapy (Chemo) in previously untreated locally advanced metastatic urothelial carcinoma (la/mUC). Ann. Oncol. 34 (Suppl. 2), S1340 (2023). DOI

Chikuma, S. et al. PD-1-mediated suppression of IL-2 production induces CD8+ T cell energy? in vivo. J. Immunol. 182, 6682–6689 (2009). PubMed DOI

Milella, M. et al. Interleukin-2 gene transfer into human transitional cell carcinoma of the urinary bladder. Br. J. Cancer 79, 770–779 (1999). PubMed DOI PMC

Sakatani, T. et al. IFN-gamma expression in the tumor microenvironment and CD8-positive tumor-infiltrating lymphocytes as prognostic markers in urothelial cancer patients receiving pembrolizumab. Cancers 14, 263 (2022). PubMed DOI PMC

Baker, S. C. et al. The urothelial transcriptomic response to interferon gamma: implications for bladder cancer prognosis and immunotherapy. Cancers 14, 5295 (2022). PubMed DOI PMC

Liu, Y. et al. Role of nectin-4 protein in cancer (Review). Int. J. Oncol. 59, 93 (2021). PubMed DOI

Chen, Z. et al. Comprehensive analysis revealed that CDKN2A is a biomarker for immune infiltrates in multiple cancers. Front. Cell Dev. Biol. 9, 808208 (2021). PubMed DOI PMC

Challita-Eid, P. M. et al. Enfortumab vedotin antibody-drug conjugate targeting nectin-4 is a highly potent therapeutic agent in multiple preclinical cancer models. Cancer Res. 76, 3003–3013 (2016). PubMed DOI

Gray, E. et al. SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models. J. Immunother. Cancer 11, e007572 (2023). PubMed DOI PMC

Ganguli, N., Kumari, P., Dash, S. & Samanta, D. Molecular and structural basis of TIGIT: nectin-4 interaction, a recently discovered pathway crucial for cancer immunotherapy. Biochem. Biophys. Res. Commun. 677, 31–37 (2023). PubMed DOI

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