Myositis International Health and Research Collaborative Alliance (MIHRA) is a newly formed purpose-built non-profit charitable research organization dedicated to accelerating international clinical trial readiness, global professional and lay education, career development and rare disease advocacy in IIM-related disorders. In its long form, the name expresses the community's scope of engagement and intent. In its abbreviation, MIHRA, conveys linguistic roots across many languages, that reflects the IIM community's spirit with meanings such as kindness, community, goodness, and peace. MIHRA unites the global multi-disciplinary community of adult and pediatric healthcare professionals, researchers, patient advisors and networks focused on conducting research in and providing care for pediatric and adult IIM-related disorders to ultimately find a cure. MIHRA serves as a resourced platform for collaborative efforts in investigator-initiated projects, consensus guidelines for IIM assessment and treatment, and IIM-specific career development through connecting research networks.MIHRA's infrastructure, mission, programming and operations are designed to address challenges unique to rare disease communities and aspires to contribute toward transformative models of rare disease research such as global expansion and inclusivity, utilization of community resources, streamlining ethics and data-sharing policies to facilitate collaborative research. Herein, summarises MIHRA operational cores, missions, vision, programming and provision of community resources to sustain, accelerate and grow global collaborative research in myositis-related disorders.

Centre for Rheumatology Division of Medicine University College London UK

CureJM Foundation Maryland USA

Department of Dermatology University of Pennsylvania and Corporal Michael J Crescenz VAMC Philadelphia PA USA

Department of Neurology University of Kansas Kansas City KS USA

Department of Neuromuscular Diseases and Centre for Rheumatology University College London; and Department of Rheumatology and Queen Square Centre for Neuromuscular Diseases University College London Hospitals NHS Foundation Trust London UK

Department of Paediatrics and Medicine Dalhousie University and IWK Health Halifax NS Canada

Department of Rheumatology and Clinical Immunology Pontificia Universidad Católica de Chile Santiago Chile

Department of Rheumatology Royal Wolverhampton Hospitals NHS Trust Wolverhampton and Division of Musculoskeletal and Dermatological Sciences Faculty of Biology Medicine and Health The University of Manchester UK

Division of Musculoskeletal and Dermatological Sciences Faculty of Biology Medicine and Health The University of Manchester and Department of Rheumatology Salford Royal Hospital Northern Care Alliance NHS Foundation Trust Manchester Academic Health Science Centre Salford UK

Division of Rheumatology University of Pittsburgh Pittsburgh PA USA

Division of Rheumatology University of Washington Seattle WA USA

Institute of Rheumatology Prague Czech Republic

Johns Hopkins Division of Rheumatology Johns Hopkins University School of Medicine Baltimore MD USA

Karolinska Medical Unit Occupational Therapy and Physical Therapy Karolinska University Hospital and Division of Rheumatology Department of Medicine Solna Karolinska Institutet Stockholm Sweden

Mayo Clinic Rochester Minnesota USA

New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center Louisiana State University and Tulane University Schools of Medicine New Orleans LA USA

Patient Research Partner New Jersey USA

Rheumatology Department at the National Hospital Alejandro Posadas University of Buenos Aires Argentina

Seattle Children's Hospital Seattle WA USA

The Myositis Association Columbia MD USA

The Myositis Association Columbia MD USA and Spierziekten Nederland Dutch Myositis Network TMA Medical Advisory Board The Netherlands

Universiteit Utrecht Utrecht The Netherlands

Walter and Eliza Hall Institute of Medical Research Melbourne Australia

Western University Ontario Canada

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