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Outcome of Conservative Treatment of Odontoid Fractures in Elderly Patients Over 80 Years Old

. 2025 ; 16 () : 21514593251315589. [epub] 20250311

Status PubMed-not-MEDLINE Language English Country United States Media electronic-ecollection

Document type Journal Article

Links

PubMed 40078446
PubMed Central PMC11898091
DOI 10.1177/21514593251315589
PII: 10.1177_21514593251315589
Knihovny.cz E-resources

INTRODUCTION: The retrospective study evaluated the clinical and radiological outcomes of conservative treatment for type II odontoid C2 fractures in octogenerians. The study aimed to assess the clinical outcomes and quality of survival of patients treated using conservative methods. Additionally, the study sought to define radiological outcomes, fracture healing success and the development of complications in correlation with clinical outcomes. MATERIALS AND METHODS: Patients aged ≥80 with dens C2 fracture were fixed with a hard cervical collar for 6 weeks, followed by early mobilization. Patients showing delayed fracture healing on computed tomography (CT) scan were subsequently immobilized in a soft neck collar for additional 6 weeks. The follow-up CT scan was then performed with consequential rehabilitation. Patients with nonunion of the C2 on the follow-up CT scan and clinical symptoms were contraindicated for physical rehabilitation for cervical spine till next CT scan after another 12 weeks. Clinical and radiographic evaluations were performed during follow-up visits, with a median follow-up was 109 days, with the range extending from 1 day to 1 year. RESULTS: In total, 33 patients were included in the study and were followed for 1 year. The 30-day mortality rate was 21.2%, and between 30 days and one year post-treatment, it was 18.2%. Mortality was higher during the study period in displaced fractures (>2 mm; 9 out of 16 patients died) compared to non-displaced fractures (≤2 mm; 4 out of 17 patients died). The Japanese Orthopaedic Association (JOA) score remained unchanged between admission (mean 16.9; SD ± 0.5) and the end of follow-up (mean 16.9; SD ± 0.5; P > 0.05), the Visual Analogue Scale (VAS) score showed improvement from values measured upon admission to the hospital (mean 7.97; SD ± 1.33) to values measured at the end of follow-up (mean 1.58; SD ± 1.62; P < 0.001) and the Neck Disability Index (NDI) showed a statistically significant difference between admission (mean 41.3; SD ± 14.92) and the end of follow-up (mean 14.29; SD ± 4.65; P < 0.001). The standard measurement of Posterior Atlantodental Interval (PADI) had an average value of 18.6 (range 16-22 mm) and primary bony union of odontoid fractures occurred in eleven cases (33.3%), while six patients (18.2%) had fibrous union with minimal clinical difficulties. CONCLUSION: This study demonstrates the safety and efficacy of conservative treatment for odontoid fractures in octogenerians and underscores the critical role of conservative management in a polymorbid elderly population.

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McIlroy S, Lam J, Khan MF, et al. Conservative management of type II odontoid fractures in older people: a retrospective observational comparison of osseous union versus nonunion. Neurosurgery. 2020;87(6):E648-E654. doi:10.1093/neuros/nyaa256 PubMed DOI

Alhashash M, Shousha M, Gendy H, Barakat AS, Boehm H. Percutaneous posterior transarticular atlantoaxial fixation for the treatment of odontoid fractures in the elderly: a prospective study. Spine. 2018;43(11):761-766. doi:10.1097/BRS.0000000000002417 PubMed DOI

Tashjian RZ, Majercik S, Biffl WL, Palumbo MA, Cioffi WG. Halo-vest immobilization increases early morbidity and mortality in elderly odontoid fractures. J Trauma. 2006;60(1):199-203. doi:10.1097/01.ta.0000197426.72261.17 PubMed DOI

Fredø HL, Rizvi SA, Lied B, Rønning P, Helseth E. The epidemiology of traumatic cervical spine fractures: a prospective population study from Norway. Scand J Trauma Resuscitation Emerg Med. 2012;20:85. doi:10.1186/1757-7241-20-85 PubMed DOI PMC

Yang Z, Yuan ZZ, Ma JX, Ma XL. Conservative versus surgical treatment for type II odontoid fractures in the elderly: grading the evidence through a meta-analysis. Orthop Traumatol Surg Res. 2015;101(7):839-844. doi:10.1016/j.otsr.2015.08.011 PubMed DOI

Greene KA, Dickman CA, Marciano FF, Drabier JB, Hadley MN, Sonntag VK. Acute axis fractures. Analysis of management and outcome in 340 consecutive cases. Spine. 1997;22(16):1843-1852. doi:10.1097/00007632-199708150-00009 PubMed DOI

Stulík J, Suchomel P, Lukás R, et al. Prímá osteosyntéza dentu--multicentrická studie [primary osteosynthesis of the odontoid process: a multicenter study]. Acta Chir Orthop Traumatol Cech. 2002;69(3):141-148. PubMed

Spiegl UJA, Keil H, Krause J, et al. Combined odontoid (C2) and atlas (C1) fractures in geriatric patients: a systematic review and treatment recommendation. Global Spine J. 2023;13(1_suppl):22S-28S. doi:10.1177/21925682221127951 PubMed DOI PMC

Hadley MN, Dickman CA, Browner CM, Sonntag VK. Acute traumatic atlas fractures: management and long term outcome. Neurosurgery. 1988;23(1):31-35. doi:10.1227/00006123-198807000-00007 PubMed DOI

Anderson LD, D'Alonzo RT. Fractures of the odontoid process of the axis. J Bone Joint Surg Am. 1974;56(8):1663-1674. PubMed

Falavigna A, Righesso O, da Silva PG, et al. Management of type II odontoid fractures: experience from Latin American spine centers. World Neurosurg. 2017;98:673-681. doi:10.1016/j.wneu.2016.10.120 PubMed DOI

Traynelis VC, Fontes RBV, Abode-Iyamah KO, Cox EM, Greenlee JD. Posterior fusion for fragility type 2 odontoid fractures. J Neurosurg Spine. 2021;35:644-650. doi:10.3171/2021.2.SPINE201645. PubMed DOI

Arnold PM, Whiting MD. Commentary: conservative management of type II odontoid fractures in older people: a retrospective observational comparison of osseous union versus nonunion. Neurosurgery. 2020;87(6):E655-E656. doi:10.1093/neuros/nyaa296 PubMed DOI

Alas H, Segreto FA, Chan HY, et al. Association between frailty status and odontoid fractures after traumatic falls: investigation of varying injury mechanisms among 70 elderly odontoid fracture patients. J Orthop Trauma. 2019;33(12):e484-e488. doi:10.1097/BOT.0000000000001597 PubMed DOI

Watanabe M, Sakai D, Yamamoto Y, Nagai T, Sato M, Mochida J. Analysis of predisposing factors in elderly people with type II odontoid fracture. Spine J. 2014;14(6):861-866. doi:10.1016/j.spinee.2013.07.434 PubMed DOI

Tenny S, Munakomi S, Varacallo M. Odontoid fractures. In: StatPearls. Treasure Island (FL). StatPearls Publishing; 2023. PubMed

Guan J, Bisson EF. Treatment of odontoid fractures in the aging population. Neurosurg Clin. 2017;28(1):115-123. doi:10.1016/j.nec.2016.07.001 PubMed DOI

Watanabe M, Sakai D, Yamamoto Y, Nagai T, Sato M, Mochida J. Analysis of predisposing factors in elderly people with type II odontoid fracture. Spine J. 2014;14(6):861-866. doi:10.1016/j.spinee.2013.07.434 PubMed DOI

Wilson C, Hoyos M, Huh A, et al. Institutional review of the management of type II odontoid fractures: associations and outcomes with fibrous union. J Neurosurg Spine. 2021;34(4):623-631. doi:10.3171/2020.8.SPINE20860 PubMed DOI

Roy-Camille R, Bleynie JF, Saillant G, Judet T. Fracture de l'odontoïde associée à une fracture des pédicules de l'axis. A propos de 11 cas [Odontoid process fractures associated with fractures of the pedicles of the axis (author's transl)]. Rev Chir Orthop Reparatrice Appar Mot. 1979;65(7):387-391. PubMed

White AA, Panjabi MM. Clinical Bbiomechanics of the Spine. 2nd ed. Philadelphia: Lippincott; 1990.

Hirabayashi K. Scoring system for cervical myelopathy (Japanese Orthopaedic Association). J Jpn Orthop Assoc. 1994;68(5):490-503.

Vernon H, Mior S. The Neck Disability Index: a study of reliability and validity. J Manip Physiol Ther. 1991;14(7):409-415. [published correction appears in J Manipulative Physiol Ther 1992 Jan;15(1):followi]. PubMed

Koller H, Kolb K, Zenner J, et al. Study on accuracy and interobserver reliability of the assessment of odontoid fracture union using plain radiographs or CT scans. Eur Spine J. 2009;18(11):1659-1668. doi:10.1007/s00586-009-1134-2 PubMed DOI PMC

Gehweiler JA. The radiology of vertebral trauma. In: John A, Gehweiler Raymond L, OsborneJr R, Becker F, eds. Saunders Monographs in Clinical Radiology, 16. Philadelphia: Saunders; 1980.

Osterhoff G, Scholz M, Disch AC, et al. Geriatric odontoid fractures: treatment algorithms of the German society for orthopaedics and trauma based on expert consensus and a systematic review. Global Spine J. 2023;13(1_suppl):13S-21S. doi:10.1177/21925682231157316 PubMed DOI PMC

Rizvi SAM, Helseth E, Aarhus M, et al. Favorable prognosis with nonsurgical management of type III acute odontoid fractures: a consecutive series of 212 patients. Spine J. 2021;21(7):1149-1158. doi:10.1016/j.spinee.2021.02.003 PubMed DOI

Smith HE, Kerr SM, Maltenfort M, et al. Early complications of surgical versus conservative treatment of isolated type II odontoid fractures in octogenarians: a retrospective cohort study. J Spinal Disord Tech. 2008;21(8):535-539. doi:10.1097/BSD.0b013e318163570b PubMed DOI

Allia J, Darmanté H, Barresi L, De Peretti F, Trojani C, Bronsard N. Early mortality and morbidity of odontoid fractures after 70 years of age. Orthop Traumatol Surg Res. 2020;106(7):1399-1403. doi:10.1016/j.otsr.2019.12.017 PubMed DOI

Honda A, Michihata N, Iizuka Y, et al. Clinical features and early post-operative complications of isolated C2 odontoid fractures: a retrospective analysis using a national inpatient database in Japan. Eur Spine J. 2021;30(12):3631-3638. doi:10.1007/s00586-021-06862-9 PubMed DOI

Huybregts JGJ, Barot KA, Recio C, Doucette J, Mekary RA, Vleggeert-Lankamp CLA. The optimal treatment of type II and III odontoid fractures in the elderly: an updated meta-analysis. Eur Spine J. 2023;32(10):3434-3449. doi:10.1007/s00586-023-07779-1 PubMed DOI

Woods BI, Hohl JB, Braly B, et al. Mortality in elderly patients following operative and nonoperative management of odontoid fractures. J Spinal Disord Tech. 2014;27(6):321-326. doi:10.1097/BSD.0b013e31825d97c4 PubMed DOI

Leister I, Haider T, Vogel M, et al. A Predictive Model to Identify Treatment-related Risk Factors for Odontoid Fracture Nonunion Using Machine Learning. Spine (Phila Pa. 1976). 2023;48(3):164-171. doi: 10.1097/BRS.0000000000004510 PubMed DOI

Harris L, Arif S, Elliot M, et al. Fusion rates for conservative and surgical management of type II odontoid fractures and its impact. Br J Neurosurg. 2021;35(5):607-610. doi:10.1080/02688697.2021.1926921 PubMed DOI

Rizvi SAM, Helseth E, Harr ME, et al. Management and long-term outcome of type II acute odontoid fractures: a population-based consecutive series of 282 patients. Spine J. 2021;21(4):627-637. doi:10.1016/j.spinee.2020.11.012 PubMed DOI

Raudenbush B, Molinari R. Longer-Term Outcomes of Geriatric Odontoid Fracture Nonunion. Geriatr Orthop Surg Rehabil. 2015;6(4):251-257. doi:10.1177/2151458515593774 PubMed DOI PMC

Rommens PM. Paradigm shift in geriatric fracture treatment. Eur J Trauma Emerg Surg. 2019. Apr; 45(2):181-189. doi:10.1007/s00068-019-01080-x PubMed DOI

Avila MJ, Farber SH, Rabah NM, et al. Nonoperative versus operative management of type II odontoid fracture in older adults: a systematic review and meta-analysis. J Neurosurg Spine. 2023;40(1):45-53. doi:10.3171/2023.6.SPINE22920 PubMed DOI

Jung MK, Hörnig L, Raisch P, et al.. Odontoid fracture in geriatric patients - analysis of complications and outcome following conservative treatment vs. ventral and dorsal surgery. BMC Geriatr. 2023. Nov; 23(1):748. doi:10.1186/s12877-023-04472-2 PubMed DOI PMC

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